The Anonymous Widower

The Recovery Trial And Coeliac Disease

The Recovery Trial appears to have been a success, with another drug announced to have positive benefits in fighting Covid-19 today.

As a coeliac on a long-term gluten-free diet like up to one-in-100 or even 1-in-50, in the UK, I wonder what they have found out about my susceptibility to Covid-19 and how my disease would affect my treatment!

I just typed “coeliac” into the Recovery Trial and I found nothing.

Using Google directly, I didn’t get any matches either.

So I suspect that they know nothing about how coeliacs are affected by Covid-19.

Since 1997, after I was diagnosed at Addenbrooke’s Hospital, I’ve been on a strict long-term gluten-free diet, my health has improved dramatically from what it was for the previous fifty years.

My only major health issue, since 1997, has been a serious stroke in 2010, from which I have made an almost full recovery.

But one cardiologist has told me, that the stroke could have been caused by fifty years of unhealthy eating, that damaged my heart muscle to cause atrial fibrillation.

I have only found one serious peer-reviewed study on coeliac disease and Covid-19 on the Internet.

This paper on the US National Library of Medicine, is from the University of Padua in Italy.

The University followed a group of 138 patients with coeliac disease, who had been on a gluten-free diet for at least six years, through the first wave of the Covid-19 pandemic in Padua.

This sentence, sums up the study.

In this analysis we report a real life “snapshot” of a cohort of CeD patients during the SARS-CoV-2 outbreak in Italy, all followed in one tertiary centre in a red area of Northern Italy. Our data show, in accordance with Emmi et al., the absolute absence of COVID-19 diagnosis in our population, although 18 subjects experienced flu-like symptoms with only one having undergone naso-pharyngeal swab.

It says that no test subject caught Covid-19, in an admittedly smallish number of patients.

But it reinforces my call for more research into whether if you are a diagnosed coeliac on a long-term gluten-free diet, you have an immune system, that gives you a degree of protection from the Covids.

How Many Patients In The Recovery Trial Are Coeliac?

The Wikipedia entry for The Recovery Trial says this about the numbers of patients.

The trial began in March 2020 and has an estimated duration through June 2021. As of December 2020, the trial had enrolled more than 20,000 COVID-19 participants admitted to hospitals in the UK.

A figure of 1-in-100 is accepted, as an at least figure of the number of coeliacs in the UK population. Some doctors rate it as high as 1-in-50.

So that should mean that somewhere between 200 and 400 of those on the trial were coeliac. But that figure would include those who were both diagnosed and undiagnosed.

I would love to have an answer to my question. But I suspect, that the data is not available.

Another Answer

There could of course be another answer – Diagnosed coeliacs on a long-term gluten-free diet don’t get the virus serious enough to go into hospital.

 

February 12, 2021 Posted by | Health | , , , | 2 Comments

Covid: Large Trial Of New Treatment Begins In UK

The title of this post, is the same as that of this article on the BBC.

These are the first three paragraphs.

A large-scale trial of a new treatment it is hoped will help stop Covid-19 patients from developing severe illness has begun in the UK.

The first patient received the treatment at Hull Royal Infirmary on Tuesday afternoon.

It involves inhaling a protein called interferon beta which the body produces when it gets a viral infection.

The product is from Synairgen and I should declare an interest.

When I heard about the company and their plans about six months ago, I made a modest four-figure investment in their shares.

I wrote about my reasons in Coronavirus: Protein Treatment Trial ‘A Breakthrough’

I have been very well rewarded.

January 13, 2021 Posted by | Health | , , | 2 Comments

Two More Life-Saving Covid Drugs Discovered

The title of this post, is the same as this article on the BBC.

With all the reporting of the shenanigans going on with Trump in the United States, this important story seems to have been buried in the news.

This is the first two paragraph of the BBC articles.

Two more life-saving drugs have been found that can cut deaths by a quarter in patients who are sickest with Covid.

The anti-inflammatory medications, given via a drip, save an extra life for every 12 treated, say researchers who have carried out a trial in NHS intensive care units.

The drugs are tocilizumab and sarilumab, which appear to be readily available.

So what was that sore-loser Trump doing?

Certainly nothing to fight the most dangerous pandemic to hit the world for a hundred years.

If he had got to grips with the pandemic in the United States, his name would have gone down in history for all the wrong reasons.

Instead, he’ll be remembered for two words beginning with I; idiot and infamy.

Is There A Link Between Tocilizumab And Coeliac Disease?

I always check new drugs proposed for the covids against coeliac disease, ever since I found that Dexamethazone could be used to treat coeliacs, who couldn’t stick to a gluten-free diet.

I found nothing for sarilumab, but I did find this article for tocilizumab (Actemra), which is entitled Will You Have Celiac Disease With Actemra?.

This is the summary.

Celiac disease is found among people who take Actemra, especially for people who are female, 50-59 old, have been taking the drug for 1 – 6 months.

The phase IV clinical study is created by eHealthMe based on reports of 55,370 people who have side effects when taking Actemra from the FDA, and is updated regularly.

Strange! Like the incorrect American spelling!

 

January 7, 2021 Posted by | Health, World | , , , , , | 5 Comments