Did This Get Lost In The Covids?
In October 2019, I wrote Asthma Carbon Footprint ‘As Big As Eating Meat’ and it made me think, when I just read it.
I would normally follow up a post like this, but I don’t remember doing anything like that.
The Wikipedia entry for the COVID-19 pandemic in England, starts with this paragraph.
The COVID-19 pandemic was first confirmed to have spread to England with two cases among Chinese nationals staying in a hotel in York on 31 January 2020.
It looks to me, that like everybody else in England, I had the Covids on my mind.
Is Respimat A Zero-Carbon Inhaler?
Just to be sure, I asked Google AI, the question in the title of this section and received this reply.
The Respimat soft mist inhaler is considered to have virtually no associated carbon emissions from its operation because it does not contain the high global warming potential (GWP) hydrofluorocarbon (HFC) propellants found in metered-dose inhalers (pMDIs).
While it has a substantially lower carbon footprint than traditional pMDIs, it is not strictly “zero-carbon” when considering its entire life cycle, which includes manufacturing, materials (stainless steel, aluminium, polymers), and end-of-life disposal. These factors contribute a small product carbon footprint (PCF).
According to Google AI, a reusable version is available.
A reusable Respimat device has been introduced, which further reduces the carbon footprint by up to 71% over six months compared to the disposable version because the device itself is kept longer, reducing manufacturing impacts.
Google AI says this about NHS guidance.
Health bodies like the NHS encourage the use of lower-carbon inhalers like the Respimat or dry powder inhalers (DPIs) as part of their net-zero targets, provided they are clinically appropriate for the patient.
But it does seem that Respimat devices are helping to cut global warming.
What Is The Patient Experience Of Respimat?
Google AI gave this answer to my question.
Patient experience with the Respimat inhaler is generally very positive, with high satisfaction for its ease of use, handling, and the “soft mist” it produces, leading to high continuation rates in studies; patients find it easier than many older devices and report good effectiveness, though common side effects like dry mouth, cough, and sore throat can occur.
Key Aspects of Patient Experience
- High Satisfaction: Over 85-90% of patients report being satisfied or very satisfied with the Respimat’s handling and the ease of inhaling the mist.
- Preference Over Other Devices: Many patients prefer Respimat over traditional metered-dose inhalers (pMDIs) or dry powder inhalers (DPIs), finding it easier to use and more effective.
- Soft Mist Technology: Patients appreciate the gentle, slow-moving mist, which helps deliver medication effectively and feels different from a typical puff.
- Good Adherence: High satisfaction often translates to continued use, with physicians reporting high patient adherence and continuation rates after studies end.
- Improved Technique: While initial use might need guidance, pharmacist-led interventions show significant improvements in patients’ inhalation technique over time.
That doesn’t look bad to me!
Could Immunotherapy Drugs Be Delivered By An Inhaler?
We always felt the device could deliver other drugs.
Google AI gave this answer to my question.
Yes, immunotherapy drugs could potentially be delivered by an inhaler, and this approach is a promising area of active research and development, particularly for treating lung cancer and respiratory diseases like asthma.
Rationale and Research
- Targeted Treatment: Inhaled delivery allows for high concentrations of the drug to be delivered directly to the lungs, which is particularly beneficial for treating lung-specific conditions like lung cancer or severe asthma. This localized approach aims to maximize the therapeutic effect where needed.
- Reduced Side Effects: By concentrating the medication in the lungs and minimizing its systemic absorption into the bloodstream, researchers hope to significantly reduce the severe side effects (e.g., systemic toxicity, autoimmune reactions) commonly associated with traditional intravenous or oral administration of some immunotherapies and chemotherapies.
- Patient Convenience: Inhalation is a non-invasive administration route, which is more convenient and comfortable for patients compared to injections or intravenous infusions, potentially allowing for self-administration and improving patient compliance.
The Soft Mist Technology could surely be a help!
Was Osborne Reynolds The Greatest Fluid Dynamicist?
I have to ask Google AI this question, as some of the discussions that led to creation of Respimat, took place in my house at Debach, where Osborne Reynolds had lived.
Google AI gave this answer to my question.
Osborne Reynolds is considered one of the most influential and foundational contributors to the field of fluid dynamics, though naming a single person the “greatest” is subjective. His work fundamentally shaped modern engineering and physics and remains central to the study of fluid flow today.
Key Contributions to Fluid Dynamics
Reynolds’ most significant achievements include:
- The Reynolds Number: He identified a crucial dimensionless parameter (now named the Reynolds number) that determines whether fluid flow is laminar (smooth and orderly) or turbulent (chaotic and eddying). This number is a foundational concept used across all engineering and physical sciences.
- The Theory of Turbulence: In an 1895 paper, he established the standard mathematical framework used in the study of turbulence, introducing what is known as the Reynolds-averaged Navier–Stokes equations.
- Experimental Validation: His elegant, yet simple, dye experiments visually demonstrated the transition between flow regimes, providing clear empirical evidence for his theories.
- Theory of Lubrication: He developed the Reynolds equation in 1886, which still underpins the analysis of hydrodynamic lubrication in modern bearings.
- Heat Transfer and Similitude: His research into heat transfer between solids and fluids led to significant improvements in boiler and condenser designs, and his work on hydraulic similitude enables engineers to use scaled-down models (e.g., in wind tunnels for aircraft design) to predict the performance of full-scale machines.
How Many Good Ideas Did The Covids Delay?
It could be that the roll-out of Respimat for was delayed by the Covids!
But it wouldn’t have been the only idea to have been delayed in that way!
The 73 Group
The 73 Group was a finance company, that I owed jointly with a guy named David Mann, who was an experienced provider of finance for cars, trucks and other vehicles and equipment.
- The company had been the idea of an accountant, I shared with David, named Graham Manning.
- David put in his expertise and I put in some of the money, I received from the sale of my share of the Artemis software.
- It operated mainly in the area around Ipswich in Suffolk.
- Many of the customers were owner/drivers, who ferried containers to and from the docks at Felixstowe, who had known David for some years.
- The company certainly gave a better return, than putting money on deposit.
- One of the things, I did was extensively model a book of loans for vehicles and this gave me an insight into the dynamics of money.
Sadly in the end, David became ill and we wound the company up.
It gave me an interesting insight into local finance and I believe, that local finance companies with good connections and the right systems and people can be profitable.
It also gave me a few good tales.
Coaches Are Good Business
A good top-of-the range coach is good business for operators, coach dealers and finance companies.
I remember spending one evening with David and a coach operator in a pub, when the operator had had a fabulous day stitching together coaches as Rail Replacement Buses for British Rail after a train derailment, between Ipswich and Colchester.
I learned a lot about operating coaches that night and it’s why I’m so keen on hydrogen-powered coaches, with their expected long range, quietness and smoothness.
Fairground Rides Are Good Business
Surprisingly, if you don’t mind being paid in fifty pence pieces on the Ipswich bypass at ten o’clock at night.
You Need A Good Collections Guy
Our’s was excellent.
UK Gov’t Tweaking CfD Rules Ahead Of 8th Allocation Round, Proposes ‘Other Deepwater Offshore Wind’ Category
The title of this post, is the same as that of this article on offshoreWIND.biz.
This is the sub-heading.
The UK government has launched a consultation on proposed refinements to the Contracts for Difference (CfD) scheme ahead of Allocation Round 8 (AR8) and future rounds, including targeted changes to the terms concerning offshore wind and floating wind projects.
These two paragraphs add more details.
The consultation, published by the Department for Energy Security and Net Zero, seeks industry feedback on contractual and eligibility adjustments, some of which are intended to reflect the increasing scale and complexity of offshore wind developments, specifically floating and other deepwater projects.
For floating offshore wind, the government is proposing changes to CfD contract terms to better align with the technology’s development timelines. These include a proposed extension of the Longstop Period to give floating wind projects more time to commission and avoid termination of their CfD contract.
The government also wants to lower the Required Installed Capacity (RIC) threshold for floating offshore wind projects.
Currently, all CfD technologies are required to deliver a minimum of 95 per cent of the capacity they have contractually agreed to install, except for (fixed-bottom) offshore wind, whose RIC is set at 85 per cent to reflect the construction risks, such as encountering unsuitable seabed conditions after work has commenced. As floating wind projects, which were so far in the range of 100 MW, have grown in scale and complexity, the government plans to apply the same RIC requirement as for fixed-bottom offshore wind.
The CfD scheme currently supports two categories of offshore wind technology: fixed-bottom offshore wind and floating offshore wind, with the regulations in use (Allocation Regulations 2014) considering only the foundation designs that float to be floating offshore wind. With the ODOW category, the government wants to make room for the novel hybrid foundation designs, “which may be suitable for deepwater deployment but do not technically float and would therefore not be considered eligible as ‘floating foundations’ under the existing legal definition of ‘floating offshore wind’.”
This last paragraph sums up the reasons for the changes.
The proposed refinements are intended to ensure the CfD scheme remains fit for purpose as offshore wind technologies evolve, while maintaining investor confidence and supporting timely project delivery.
Hopefully developments at ports like Belfast, East Anglia, Inverness & Cromarty FreePort,Lowestoft and Tyne will encourage to develop wind farms around the shores of the UK.
The Anonymous Widower 