Did This Get Lost In The Covids?
In October 2019, I wrote Asthma Carbon Footprint ‘As Big As Eating Meat’ and it made me think, when I just read it.
I would normally follow up a post like this, but I don’t remember doing anything like that.
The Wikipedia entry for the COVID-19 pandemic in England, starts with this paragraph.
The COVID-19 pandemic was first confirmed to have spread to England with two cases among Chinese nationals staying in a hotel in York on 31 January 2020.
It looks to me, that like everybody else in England, I had the Covids on my mind.
Is Respimat A Zero-Carbon Inhaler?
Just to be sure, I asked Google AI, the question in the title of this section and received this reply.
The Respimat soft mist inhaler is considered to have virtually no associated carbon emissions from its operation because it does not contain the high global warming potential (GWP) hydrofluorocarbon (HFC) propellants found in metered-dose inhalers (pMDIs).
While it has a substantially lower carbon footprint than traditional pMDIs, it is not strictly “zero-carbon” when considering its entire life cycle, which includes manufacturing, materials (stainless steel, aluminium, polymers), and end-of-life disposal. These factors contribute a small product carbon footprint (PCF).
According to Google AI, a reusable version is available.
A reusable Respimat device has been introduced, which further reduces the carbon footprint by up to 71% over six months compared to the disposable version because the device itself is kept longer, reducing manufacturing impacts.
Google AI says this about NHS guidance.
Health bodies like the NHS encourage the use of lower-carbon inhalers like the Respimat or dry powder inhalers (DPIs) as part of their net-zero targets, provided they are clinically appropriate for the patient.
But it does seem that Respimat devices are helping to cut global warming.
What Is The Patient Experience Of Respimat?
Google AI gave this answer to my question.
Patient experience with the Respimat inhaler is generally very positive, with high satisfaction for its ease of use, handling, and the “soft mist” it produces, leading to high continuation rates in studies; patients find it easier than many older devices and report good effectiveness, though common side effects like dry mouth, cough, and sore throat can occur.
Key Aspects of Patient Experience
- High Satisfaction: Over 85-90% of patients report being satisfied or very satisfied with the Respimat’s handling and the ease of inhaling the mist.
- Preference Over Other Devices: Many patients prefer Respimat over traditional metered-dose inhalers (pMDIs) or dry powder inhalers (DPIs), finding it easier to use and more effective.
- Soft Mist Technology: Patients appreciate the gentle, slow-moving mist, which helps deliver medication effectively and feels different from a typical puff.
- Good Adherence: High satisfaction often translates to continued use, with physicians reporting high patient adherence and continuation rates after studies end.
- Improved Technique: While initial use might need guidance, pharmacist-led interventions show significant improvements in patients’ inhalation technique over time.
That doesn’t look bad to me!
Could Immunotherapy Drugs Be Delivered By An Inhaler?
We always felt the device could deliver other drugs.
Google AI gave this answer to my question.
Yes, immunotherapy drugs could potentially be delivered by an inhaler, and this approach is a promising area of active research and development, particularly for treating lung cancer and respiratory diseases like asthma.
Rationale and Research
- Targeted Treatment: Inhaled delivery allows for high concentrations of the drug to be delivered directly to the lungs, which is particularly beneficial for treating lung-specific conditions like lung cancer or severe asthma. This localized approach aims to maximize the therapeutic effect where needed.
- Reduced Side Effects: By concentrating the medication in the lungs and minimizing its systemic absorption into the bloodstream, researchers hope to significantly reduce the severe side effects (e.g., systemic toxicity, autoimmune reactions) commonly associated with traditional intravenous or oral administration of some immunotherapies and chemotherapies.
- Patient Convenience: Inhalation is a non-invasive administration route, which is more convenient and comfortable for patients compared to injections or intravenous infusions, potentially allowing for self-administration and improving patient compliance.
The Soft Mist Technology could surely be a help!
Was Osborne Reynolds The Greatest Fluid Dynamicist?
I have to ask Google AI this question, as some of the discussions that led to creation of Respimat, took place in my house at Debach, where Osborne Reynolds had lived.
Google AI gave this answer to my question.
Osborne Reynolds is considered one of the most influential and foundational contributors to the field of fluid dynamics, though naming a single person the “greatest” is subjective. His work fundamentally shaped modern engineering and physics and remains central to the study of fluid flow today.
Key Contributions to Fluid Dynamics
Reynolds’ most significant achievements include:
- The Reynolds Number: He identified a crucial dimensionless parameter (now named the Reynolds number) that determines whether fluid flow is laminar (smooth and orderly) or turbulent (chaotic and eddying). This number is a foundational concept used across all engineering and physical sciences.
- The Theory of Turbulence: In an 1895 paper, he established the standard mathematical framework used in the study of turbulence, introducing what is known as the Reynolds-averaged Navier–Stokes equations.
- Experimental Validation: His elegant, yet simple, dye experiments visually demonstrated the transition between flow regimes, providing clear empirical evidence for his theories.
- Theory of Lubrication: He developed the Reynolds equation in 1886, which still underpins the analysis of hydrodynamic lubrication in modern bearings.
- Heat Transfer and Similitude: His research into heat transfer between solids and fluids led to significant improvements in boiler and condenser designs, and his work on hydraulic similitude enables engineers to use scaled-down models (e.g., in wind tunnels for aircraft design) to predict the performance of full-scale machines.
How Many Good Ideas Did The Covids Delay?
It could be that the roll-out of Respimat for was delayed by the Covids!
But it wouldn’t have been the only idea to have been delayed in that way!
I’ve Just Come Across Avnos
I feel we should take into account any possibilities of second use of oil or gas structures, that once held hydrocarbons.
An article in a magazine called Carbon Herald pointed me to a company called Avnos, who are developing Direct Air Capture of carbon dioxide out of the atmosphere. If systems like that of Avnos do work, we may need somewhere to put the carbon dioxide.
Centrica are storing the hydrogen in the Rough gas field, which was previously used for storing natural gas and now some depleted gas fields are being used to store captured carbon dioxide.
On the subject of carbon capture, Avnos do it differently, in that for every tonne of CO2, they capture from the air, they capture five tonnes of distilled water. And they do it without using any heat.
This is their web site.
This is their mission statement on the front page of the web site. There is also a video.
Carbon Negative. Water Positive
Avnos is commercializing the most advanced technology in the Direct Air Capture of CO2
Our proprietary Hybrid Direct Air Capture (HDAC) solution inverts the water paradigm in DAC, producing water, eliminating heat consumption and reducing costs compared to other forms of DAC.
It sounds too good to be true!
But I have experience of the positive financial results of fluid dynamics in this area.
Thirty years ago, two guys approached me with an idea for an aerosol valve that used nitrogen as a propellant.
At the time, I lived in the house, where Osborne Reynolds, the great Victorian fluid dynamicist of Reynold’s number fame had been brought up.
The guys succeeded and the device was sold on to J & J.
They were then asked to develop a metered dose inhaler for asthma drugs, which is now sold as Respimat, which is sold by Boehringer Ingelheim.
Afterwards, I researched Reynolds at Manchester University, where he was the first Professor of Engineering and I found that he had done some marvelous things with fluids. He was a true genius and undergraduates are still taught on his Victorian apparatus.
I suspect that Avnos may have been exploring in the same area and are using another of Reynold’s useful properties.
This Hydrogen Engine From Kia And Hyundai Heralds A New Dawn In Automotive – Everything Will Change – Lagrada
The title of this post, is the same as that of this article on Hydrogen Central.
These are the first two paragraphs.
Hyundai and Kia recently unveiled in Korea a zero-emission hydrogen engine that could disrupt the EV market. Both automakers are at the forefront of the development of hydrogen technology, focusing on both fuel cell systems and investigating the possibilities of sophisticated hydrogen engines.
The future of sustainable mobility is being shaped by Hyundai and Kia’s continuous research and dedication to hydrogen as a clean transportation solution. An increasing number of manufacturers are developing hydrogen engines as an alternative to electric cars and vehicles that use polluting combustion engines.
These three paragraphs outline more details of the engine.
What’s more remarkable about this new hydrogen engine presented in Korea is that it solves all the problems of durability and large-scale viability that hydrogen engines have presented until now.
The project team successfully ensured that the Hyundai-Kia hydrogen engine, designed to burn hydrogen, could sustain high thermal efficiency throughout its operation by infusing hydrogen into the combustion chamber at a pressure of 30 bar.
Although the device’s performance was enhanced by the use of a turbocharger, it was found that the enhanced performance and lower pollution emissions of this kind of “direct injection” eliminated the problems that most automakers have with hydrogen engines. As the emissions of carbon dioxide and fine particles were reduced by 99% and 90%, the Hyundai-Kia hydrogen engine would be considered to have zero emissions.
Thirty years ago, I was involved with a company called DMW.
- The company’s first product was an aerosol valve, that instead of using CFCs or HCFCs as a propellent used nitrogen. The patent was sold to Johnson and Johnson, after being shown during the discussions, that led to the Montreal Protocol and the phase out of CFCs.
- This led to a deal with Glaxo to investigate if DMW’s technology could be used in a metred-dose-inhaler for asthma drugs.
- The successful idea was eventual sold to Boehringer Ingelheim and is now marketed as Respimat.
I can compare the Hyundai-Kia hydrogen injector and the Respimat inhaler
- Hyundai-Kia appear to be using a high pressure of 30 bar to sustain high-thermal efficiency.
- I know that the Respimat inhaler uses high pressure to obtain a fine mist of the drug.
It sounds to me, that both companies are using the same properties of applying high pressure to a small hole, to disperse one fluid in another.
The Economic Case For Hydrogen In Domestic Heating
The title of this post, is the same as that of this article on The Chemical Engineer.
The Wikipedia entry for The Chemical Engineer has this introductory paragraph.
The Chemical Engineer is a monthly chemical engineering technical and news magazine published by the Institution of Chemical Engineers (IChemE). It has technical articles of interest to practitioners and educators, and also addresses current events in world of chemical engineering including research, international business news and government policy as it affects the chemical engineering community. The magazine is sent to all members of the IChemE and is included in the cost of membership. Some parts of the magazine are available free online, including recent news and a series of biographies “Chemical Engineers who Changed the World”, although the core and the archive magazine is available only with a subscription. The online magazine also has freely available podcasts.
It is a source on the Internet, where anything non-scientifically correct will be unlikely to appear.
The article has two introductory sub-headings.
Despite its thermodynamic disadvantages, global energy technology specialist Thomas Brewer believes hydrogen has an economic and efficient role in domestic heating. It forced him to deviate from his usual mantra of ‘efficiency above all else’ to get there, though
The work of decarbonisation by chemical engineers is about how we can cost effectively enable our organisations’ transition away from fossil fuels. This requires foresight. A decision chemical engineers make on a project with a 20-year lifespan will still be operational in 2045, when in most global locations, internal combustion engine (ICE) vehicles will probably be in the minority and grid electricity will be mostly renewable.
This is the first actual paragraph.
It is unsurprising, therefore, that chemical engineers are researching and debating the prospects of the future of energy availability from renewables, and the likely role and cost of hydrogen. There is much public noise surrounding the conversation about heat pumps vs hydrogen for domestic heating. I have noticed how few articles are written from an unbiased perspective, how very few reports talk about the whole solution, and authors avoid quantifying the financial impact of their proposed solution. I couldn’t find an unbiased study with any financial logic, so, I built a model to assess the options, for my own interests. I found the results so intriguing that I wanted to share them.
In other words, let the data do the talking and accept what it tells you.
These are some extracts from the article.
On Curtailment
The article says this on curtailment of wind energy, because you are generating too much.
Efficient electrical energy storage is expensive, which has traditionally led renewable system designers to include curtailment as a part of their design. Curtailment involves oversizing the wind supply to be higher than the grid connection to reduce the need for as much energy storage, and deliberately wasting the occasional electrical excess. The system design becomes an economical balance between oversizing the renewable generation and paying for additional electrical storage. Within the UK grid in 2023, curtailment is a small factor. As electrification and wind power become more mainstream, the financial decision between investing in excess wind vs electrical storage will lead curtailment to become a more significant factor.
Curtailment is to me a practice, that should be consigned to the dustbin of history.
To eliminate it, as much storage as is needed storage must be provided.
Eliminate Naked Flames In The Kitchen
The article says this about eliminating naked gas flames (natural gas or hydrogen) in the kitchen.
Figure 1 shows that the recommended standard of hydrogen gas installation if removing kitchen gas cooking would result in less injuries than the existing natural gas installation if cooking were converted to induction heating. Kitchen leaks are more likely than boiler leaks due to the number of valves and connections, regardless of the gas type. NOx emissions in the home because of naked flames in the kitchen are also of concern to the health of the occupants and hydrogen naked flames have a higher NOx emission than natural gas; another reason to eliminate naked flame cooking.
When I was financing the development of what became the Respimat inhaler, I did my due scientific diligence and found research from a Russell Group University, that naked flames (including smoking) were a cause of asthma, especially in children.
My recommendation is that, at an appropriate time in the near future, you replace your gas cooker with an electric one. My ginger-haired Glaswegian friend, who is a chef, who’s had Michelin stars would recommend an electric induction cooker.
Pumped Storage
The article says this about building more pumped storage.
The pumped storage assumption is based on the SSE proposal for Coire Glas, a 30 GWh £1.5bn storage system in Scotland which will more than double the UK’s current pumped storage capacity. The capital cost of this pumped storage system is about £50/kWh which will be delivered at about 80% efficiency. Pumped storage is a good balance between low cost and high efficiency. However, it requires natural resources. The Mott MacDonald report, Storage cost and technical assumptions for BEIS (Department for Business, Energy and Industrial Strategy) suggests the equivalent of four Coire Glas-scale installations in the UK by 2050. The model optimistically assumes that ten more similar additional Coire Glas-size pumped storage schemes could be installed.
This page on the Strathclyde University web site, gives these GWh figures for the possible amounts of pumped-storage that can be added to existing hydroelectric schemes.
Strathclyde’s total for extra storage is over 500 GWh.
Distributed Batteries
The article says this about distributed batteries.
A distributed battery assumption could be configured with multiple 10 kWh batteries which typically cost about £3,000 installed, near or in homes with a heat pump. This could be coupled with larger battery storage systems like the £30m Chapel Farm 99 MWh battery installation near Luton, commissioned in 2023. The small battery systems at each home are similar to the proposed virtual power plants using electric vehicle battery capacity to help balance the grid. Placing these batteries at locations with grid limitations could reduce the costs of upgrading the grid system. This is a more expensive energy storage scheme than pump storage and for the purposes of the model it is assumed that battery storage schemes are limitless. In both cases cited, the cost is £300/kWh. Battery efficiency varies significantly with temperature, and typically ranges from about 90% to 97%. As the system design needs to be focused on the coldest periods, the model is optimistically assuming 93% efficiency, which would require many of the batteries to be in a heated environment.
New lower-cost alternative batteries are also being developed.
Hydrogen Generation
The article says this about hydrogen generation.
Alternatively, the electricity generated from wind energy could be used in the electrolysis of water to produce hydrogen. While the fully installed electrolysis equipment costs about £2,100/kW, hydrogen storage in specially built cylinders is relatively cheap at about £23/kWh. The model, however, assumes salt mine storage which the US DoE in their report, Grid Energy Storage Technology Cost, calculate at a total system cost for hydrogen of $2/kWh. Electrolysis is the least efficient energy storage option, with a conversion efficiency of 75%, including compression. The waste heat from this conversion loss is useful for industrial heating, or in a district heating system. This has been ignored for simplicity.
Pumped storage, distributed batteries and hydrogen electrolysers distributed all over the UK, will mop up all the spare electricity and release it to heat pumps and for charging cars as necessary.
The hydrogen will be used for heating, to decarbonise difficult-to-decarbonise industries and provide fuel for hydrogen-powered vehicles, railways and shipping.
Curtailment will be a thing of the past.
The UK Offshore Wind Potential
The article says this about the UK offshore wind potential.
The UK government target for wind generation by 2030 is 50 GW. The UK offshore wind potential is reliable and available and has been estimated to be as high as 2,200 GW. There are, however, a few low wind periods that can last for several days.
I am not going to argue with 2,200 GW, but I will say that a lot of that will be used to generate hydrogen offshore.
Conclusions
This is the article’s main conclusion.
A wind-based supply for heating will mean that large quantities of potentially unused electricity will be available for more than 90% of the year, for potentially very low cost. While this could appear wasteful, it provides further synergistical opportunities for the decarbonisation of other interruptible energy duties, such as production of hydrogen for road transport or supplying heat via heat pumps for interruptible industries.
The sensitivity analysis shows that these conclusions are robust even with significant variation in the assumptions on equipment cost, efficiency, and other electricity source options.
This is also said about the most cost-effective solution.
A cost-effective national heat pump-only solution is about £500bn (50%) more expensive than a hydrogen-only boiler solution. The most cost-effective system is a combination of the two, £100bn cheaper than the hydrogen-only solution, and £600bn cheaper than the heat pump-only solution.
A cost-effective national heat pump-only solution has a system efficiency 40% lower than the hydrogen-only solution, requiring more than 750 GW of installed wind capacity. A hydrogen boiler solution requires less than 500 GW but the most efficient system, however, is a combination of the two.
The conclusions mean that everybody will be able to use the most appropriate solution for their circumstances for both heating their housing or powering their vehicles, as there will be massive supplies of affordable electricity and hydrogen.
How Will Everything Be Paid For?
Just as Germany and others built its industry on cheap Russian gas, it will now choose to use the plentiful and reliable UK electricity and hydrogen to rebuild its industry.
Wood Burning At Home
The title of this post, is the same as that of the title on the home page of this web site.
I actually accessed the page as it appeared as an advert on something I was looking at on the Internet.
This is the sub-heading.
How do you feel about open fires, wood burners and even wood smoke?
These four paragraphs make up the home page.
It has long been known that the small particles released by solid fuel burning can stay in the air and even travel long distances. These small particles, when inhaled, can increase your risk of stroke, asthma, lung cancer, heart disease and dementia.
It is estimated that around 4,000 premature deaths occur each year in London due to long-term exposure to air pollution, of which about 284 are attributable to domestic wood burning. Every one of those 284 deaths is completely avoidable.
Domestic wood burning has a health and economic cost of about £187 million per year in London. That’s a cost of £24 for every London resident, whether you burn solid fuels or not.
The most effective way of reducing pollution and protecting everyone’s health is simply to avoid burning any wood, coal, or other solid fuels at home.
As I don’t have naked flames at all in my house, this doesn’t apply to me.
When I helped to fund two guys, who were developing a metered dose inhaler for asthma drugs, I did my due diligence before I invested.
I found some research, that said that naked flames and the oxides of nitrogen they produce, were one of the main causes of asthma.
So I avoid them and don’t do barbecues, bonfires, gas cookers or gas fires.
Incidentally, the two guys did develop the metered dose inhaler for asthma drugs and it is now prescribed as Respimat. It is totally mechanical, with no compressed gases or batteries.
Vineyard Wind To Deploy US-Based Supplier’s Bubble Curtain During Foundation Installation
The title of this post, is the same as that of this article on offshoreWIND.biz.
This is the sub-heading.
Vineyard Wind, a joint venture between Copenhagen Infrastructure Partners (CIP) and Avangrid building the first large-scale offshore wind farm in the US, has signed an agreement with the US company ThayerMahan for a pilot programme to deploy and test a secondary bubble curtain during the installation of foundations
This is the first paragraph.
A bubble curtain mitigates noise created during foundation installation by absorbing and dampening sound. First, the curtain’s large, perforated hoses are placed on the seafloor around the monopile. Then, the hoses are filled with compressed air which, once the hoses are inflated, escapes through the perforations and creates a barrier of bubbles that reduce noise.
Nothing is said, as to how the bubbles cut the noise.
I’m fairly certain that I know why.
- The speed of sound in air on a standard day at sea level static conditions, is about 340 metres/second.
- In water it’s about 1500 metres/second.
So what would the speed of sound in a bubbly mixture of air and water be?
I asked this question of Google and got this answer.
Surprisingly, in a two- fluid mixture, the measured speed of sound can be one order of magnitude smaller than that of its constituents. For example for water and air in normal conditions the speed of sound in the mixture can be about 23m/s while it is 1500m/s in water and 330m/s in air.
I even made money out of this phenomena, by backing two guys, who used it to develop an aerosol valve that used nitrogen as a propellant.
This research indirectly led to the development of the Respimat inhaler for asthma drugs.
So how does it cut the noise?
I’m not sure of this, but we do know the noise of the piling will have to go through areas of water with different speeds of sound. So is the sound attenuated as it passes through the bubble curtain by the slow speed?
I have other ideas for this interesting phenomenon and if anybody is interested please contact me. One use may have applications in mixing dissimilar fluids.
Coeliac Journey Through Covid-19 – Introduction
Introduction
I am coeliac and I had an interesting journey through the Covid-19 pandemic.
My experiences will be laid out in this narrative, as I believe they might be of use to someone.
I was born in 1947 and after a good education at Minchenden Grammar School in North London, I read Electrical Engineering and Electronics at Liverpool University, where in addition to getting a B. Eng degree, I met and married my late wife; Celia. We had three boys in the early seventies.
My working life was mainly spent in the solving of mathematical problems and writing software to perform complex calculations mainly in the fields of data analysis, project management, statistics and the solving of simultaneous differential equations.
The Artemis software, that I wrote in the 1970s, controlled the building of the Channel Tunnel, was the software of choice in the development of the North Sea oil and gas fields and was even used by NASA to plan the missions of the Space Shuttles and their refurbishment after each flight.
My business partners and myself sold the company to the American aerospace company; Lockheed in the 1980s.
Since then, I have been involved in various ventures.
The most successful was to back two inventors, who had developed an aerosol valve that used nitrogen as the propellant.
We sold that on to Johnson & Johnson, but the experience led to the development of the Respimat Inhaler for Boehringer Ingelheim.
Multi-Turbine Windcatcher Secures More Funding
The title of this post, is the same as that of this article on offshoreWIND.biz.
This is the sub-heading.
Norway’s Wind Catching Systems AS, the developer of the Windcatcher floating offshore wind technology, has secured a pre-project grant of NOK 9.3 million (USD 0.9 Million) from ENOVA.
The Windcatcher certainly looks impressive on the home page of the Wind Catching Systems AS web site.
This image is of the over-station development at Moorgate station.
If this structure is strong enough to hold up an eight floor building, surely a system can be designed to hold up a number of small wind turbines.
But will it work well in practice or is it just something that looks good in a visualisation?
Note that aerodynamics and fluid flow are difficult subjects to model on a computer, as I say from experience of getting nowhere, when I tried to mathematically model a plastic extruder at ICI in the early 1970s.
But I did successfully invest in two guys, who went on to develop the Respimat inhaler for Boehringer Ingelheim.
So I have had mixed success in dealing with these tricky subjects.
When I look at the Windcatcher, I think there’s a fifty-percent chance, that it will be a success and a lot depends on the investors.
I do wish the company well and I feel it in my bones, that a couple of weird turbine designs will be runaway successes.
Asthma Carbon Footprint ‘As Big As Eating Meat’
The title of this post is the same as that of this article on the BBC.
This is the introductory paragraph.
Many people with asthma could cut their carbon footprint and help save the environment by switching to “greener” medications, UK researchers say.
I know more than a bit about metered dose inhalers.
I backed an inhaler, which is marketed under the name of Respimat, as when I saw the technology of the company, my physics knowledge told me that they had something.
The device was purely mechanical, with no batteries, electrical supply, gases or noxious chemicals. It effectively used the principle of an old-fashioned air pistol, that fired drugs instead of pellets.
I still have the prototype in my garage.
It was a bit of a roller-coaster of an investment, but I made a good return in the end, when we sold the device to Bohringer Ingelheim.
I was saying what Cambridge University are now saying, nearly twenty years ago!
The Anonymous Widower 