Hospital Pioneers Cancer Service For Over 70s That Saves Lives And Money
The title of this post, is the same as that of this article in The Times.
This is the sub-heading.
Treatment is adapted to take into account age-related illnesses, such as heart disease, diabetes and dementia.
These three paragraphs outline, what the Christie Hospital is doing.
The Christie Hospital in Manchester is pioneering a specialist cancer service for elderly patients under plans to tackle a “silver tsunami” of cases.
More than 200 patients have been treated by the new team, which was set up to meet the more complex care needs of an ageing population.
The service has nearly halved the number of unplanned hospital admissions among older cancer patients, improving survival and quality of life.
But it’s the graph that follows that I find interesting.
It shows the cancer incidence rate (per 100,000 population) in 2020 by gender and age at diagnosis.
I am a control engineer and statistician and one of the most interesting things in a graph like this is the rate of increase or in this graph’s case the rate of decrease, as the graph effectively has the present at the top.
I have used an old trick and looked at the difference between the groups and the difference between the difference.
Note.
- It seems that the rate of increase of cancer diagnosis with age seems to increase with ages of 60-64 and 25-29.
- This would seem to correspond to those born before 1960 and those born before 1995.
- As a coeliac, I know that the first test for coeliac disease, which used endoscopy was introduced around 1960.
- The modern genetic test for coeliac disease was developed in the 1990s.
Is it coincidence, that the rate of increase of cancer diagnosis with age seems to increase, when a better diagnosis for coeliac disease was introduced?
These are my thoughts!
Coeliac Disease And Me
I am coeliac and I was born in 1947. I wasn’t diagnosed as coeliac until 1997.
I was an unhealthy child, with all sorts of avenues being chased, so in the end they just took my tonsils out.
- It should be remembered, that there was no test for coeliac disease in children until 1960.
- I’ve also only met one coeliac older than me and both her parents were GPs and she was diagnosed by food elimination.
- In fact, I never met a coeliac until I was about 25. He was the two-year-old son of one of C’s friends.
At fifty, an elderly locum gave me a present of a blood test to clear up my long-term health problems. The results showed that my body had very little Vitamin B12. Injections didn’t improve the level, so my GP sent me to Addenbrooke’s.
It was a Monday and all the consultant did was ask a nurse to take several vials of blood. He didn’t ask me any relevant questions or even touch me.
On the Wednesday morning, I got a letter from the hospital saying I was probably coeliac and it would be confirmed by endoscopy.
I must have been one of the first to have been diagnosed by a genetic test on a sample of blood.
Coeliac Disease And My Youngest Son
My youngest son was born in 1972 and after my diagnosis, my late wife felt he was coeliac, as physically he was so like me. But neither him nor our other two sons would get themselves tested.
I am now sure he was coeliac, as his daughter was born with a congenital hernia of the diaphragm and Swedish research says can happen with coeliac fathers. Luckily, she was born in the Royal London Hospital and thanks to heroic surgery at a few days old, she survived and is now in her first year at Southampton University.
Sadly my youngest son died of pancreatic cancer in 2011.
Coeliac Disease And Cancer
Nottingham University have shown that if you are coeliac and stick to a gluten-free diet, you are twenty-five percent less likely to suffer from cancer.
Cancer in the Over Sixties
The following is an extract from A Thought On Deaths Of The Elderly From Covid-19, which I wrote in April 2020.
How many undiagnosed coeliacs are there in those over seventy, who because they are coeliacs, have a compromised immune system?
I would be undiagnosed but for that elderly locum!
How many other coeliacs are there in the UK population?
- Age UK has a figure of twelve million who are over 65 in the UK.
- If 1-in-100, as stated by Coeliac UK, in the UK are coeliac, that is 120,000 coeliacs over 65, who are too old to have been diagnosed as a child, because no test existed.
Note that as of today 177,388 have been diagnosed with Covid-19.
Could the drop in the cancer rate of those born before 1960 be because of the availability of a test for coeliac disease, so that if they were a sickly child like me, they would be diagnosed? As I said earlier diagnosed coeliacs have a lower cancer rate than the general population.
Cancer in the Under Thirties
I was diagnosed in 1997 by a genetic blood test and there is no doubt that I have coeliac disease.
As the test is so simple, I wonder what proportion of coeliacs born since the Millennium have been diagnosed.
And how does this contribute to the drop in cancer cases?
More Research Needs To Be Done
It is obvious to me, that research needs to be done into the link between undiagnosed coeliacs and cancer.
It might be prudent to test every cancer patient for coeliac disease. My GP told me, that the test is not expensive and generally gives the right result.
Positive Traction Launches 08e – “The Future Of Sustainable Depot Operations”
The title of this post is the same as this article on Rail UK.
This is the first two paragraphs.
Positive Traction has launched the UK’s first re-engineered battery powered shunting locomotive – the 08e.
Free from carbon, NOx and particulate emissions the 08e can fulfil day-to-day operating needs as well as meet the demanding ESG requirement of shareholders, customers, employees and neighbouring communities.
Note.
- 996 Class 08 locomotives were originally produced between 1952 and 1962.
- Around a hundred are still in use on the UK rail network.
- This page on the Positive Traction web site, gives more details.
This could be a sensible use of technology, that carves itself a profitable niche market.
Rolls-Royce Completes Next Step On Its Journey To Decarbonising Business Aviation
The title of this post, is the same as that of this press release from Rolls-Royce.
This is the sub-heading.
Rolls-Royce today announces the successful completion of a series of tests with 100% Sustainable Aviation Fuel (SAF) on its latest generation of business aviation engines, the Pearl 15 and the Pearl 10X. The Pearl 15, the first member of the Pearl engine family, powers Bombardier’s Global 5500 and 6500 aircraft, while the Pearl 10X will power Dassault’s ultra-long-range flagship aircraft, the Falcon 10X.
These are the websites for the three aircraft, with number of passengers, typical cruise speed and range.
- Bombardier Global 5500 – 16 pax – Mach 0.85 – 5900 nm
- Bombardier Global 6500 – 17 pax – Mach 0.85 – 6600 nm
- Dassault Falcon 10X – 19 pax – Mach 0.925 – 7500 nm
This screenshot from the Dassault Falcon 10X web site shows the range from London.
Note that Buenos Aires, the Falkland Islands, Seattle, Seoul and Tokyo are all within range.
I have a few thoughts and observations.
Jet A-1 And 100% SAF
This paragraph from the press release describes how Rolls-Royce are testing the compatibility of Jet A-1 and 100% SAF.
As well as proving compatibility with 100% SAF another target of the test campaign was to run a back-to-back engine test with both Jet A-1 and SAF on the same Pearl 10X engine. The aim was to confirm further improvements in the environmental footprint when switching to SAF. The results from this first back-to-back engine emission test under standard certification conditions provides important correlations for the evaluation of future SAF within our environmental strategy.
Compatibility and back-to-back running is surely very important, as it could be many years before all airports can supply 100 % SAF for visiting jet aircraft.
The Fuels Used In The Tests And The Benefits
These two paragraphs from the press release describes the fuels used and the benefits..
The HEFA (Hydro-processed Esters and Fatty Acids) SAF was produced from waste-based sustainable feedstocks such as used cooking oils and waste fat. This fuel has the potential to significantly reduce net CO2 lifecycle emissions by about 80% compared to conventional jet fuel.
The back-to-back tests conducted with conventional fossil-based fuel and subsequently SAF also confirmed a cleaner combustion of the sustainable fuel, with significantly lower levels of non-volatile particulate matter (nvPM). In combination with the low NOx combustor technology of the Pearl 10X and its additive manufactured combustor tiles a reduction of all emissions was achieved.
Note.
- An eighty percent reduction in lifecycle emissions is not to be sneezed at.
- Cleaner combustion and low NOx emissions are very much bonuses.
- Additive manufacture is better known as 3D-printing and I’m not surprised that Rolls-Royce have embraced the technology.
As an engineer and retired light aircraft pilot, I suspect the tests have met Rolls-Royce’s objectives.
Moving To 100 % SAF
This is the final paragraph of the press release.
The tests demonstrated once again that Rolls-Royce’s current engine portfolio for large civil and business jet applications can operate with 100% SAF, laying the groundwork for moving this type of fuel towards certification. At present, SAF is only certified for blends of up to 50% with conventional jet fuel. By the end of 2023 Rolls-Royce will have proven that all its in-production Trent and business aviation engines are compatible with 100% SAF.
It must be a good selling point for aircraft equipped with Rolls-Royce engines, that the buyer knows that the aircraft can run on 100% SAF.
100 % SAF As An Airline Marketing Tool
It will be interesting to see how airlines use 100% SAF to sell tickets.
As an example, I can see routes like London and Scotland becoming very competitive.
- Avanti West Coast, LNER and Lumo already run all-electric trains to Edinburgh and Glasgow.
- The technology exists to decarbonise trains to Aberdeen and Inverness..
- Other open access operators could well move in to a lucrative market.
- The only way, that the airlines will be able to compete on emissions, would be to move to 100 % SAF.
There must be hundreds of routes like London and Scotland around the world.
100 % SAF And Business Jets
In A Class 319 Train, But Not As We Know It!, I told this tale.
I am reminded of a tale, that I heard from a former GEC manager.
He was involved in selling one of GEC’s Air Traffic Control radars to a Middle Eastern country.
The only working installation of the radar was at Prestwick in Scotland, so he arranged that the dignitaries and the sales team would be flown to Prestwick in GEC’s HS 125 business jet.
As they disembarked at Prestwick and walked to the terminal, the pilot called the GEC Manager over.
The pilot told him “The Scottish Highlands at this time of the year, are one of the most beautiful places in the world! Would you and your guests like a low-level tour on the way back? I can arrange it, if you say so!”
Despite knowing GEC’s draconian attitude to cost control he said yes.
The sale was clinched!
I also remember an article in Flight International about how JCB sold diggers.
- Dealers in a country like Greece would put together a party of prospective customers.
- The customers would then be flown to East Midlands Airport in JCB’s business jet, which is close to the JCB factory at Rocester.
- After a sales demonstration and a tour of the factory they would be flown home.
I once met a lady who had been one of JCB’s cabin staff and she told me it was a very successful sales technique.
I suspect that a business jet running on 100 % SAF would be an even better sales aid.
There are also increasing protests from the greens about business jets, which are seen as producing pollution and are only the toys of the rich and powerful.
Surely, if they were running on 100 % SAF, this would make business jets more acceptable.
100 % SAF And Niche Airlines
In the web site for the Falcon 10X, there is a section called Mission Flexibility, where this is said.
As large as it is, the Falcon 10X can still access typical airports serving business aviation as well as others with challenging approaches. The Falcon 10X will be London City-capable so that it can fly you straight into the heart of global finance. When you’re ready for rest and relaxation, the 10X can whisk you to out-of-the-way corners of the world.
British Airways used to run a service between London City Airport and New York.
- The route used 32-seat Airbus A-318 airliners.
- The flight stopped at Shannon for refuelling.
- It was business class only.
I suspect someone will think about running a similar London City Airport and New York service using a Falcon 10X.
- It has nineteen seats.
- It could do it in one hop.
- It could run on 100 % SAF.
- British Airways must have all the passenger data from the discontinued service.
- A Falcon 10X flies higher than a Boeing 767, Boeing 787 or an Airbus A350.
I have a feeling that flight time would be comparable or better to a flight between Heathrow and New York.
Conclusion
Rolls-Royce would appear to have the right strategy.
If I was going to New York in business class, I’d use it.
Is There A Research Dermatologist Out There?
Consider.
- I have mused about my skin before in My Strange Skin.
- I have been feeling a bit odd because of Babet.
- I have had problems with my left humerus for a few days now and my left hand has not been very co-operative.
- Yesterday, I kept dropping my bag for a start.
- Last night, I needed to go to the loo in the middle of the night. I could hardly walk, because of pain in my right lower leg.
- But I’d forgotten to put the magic Udrate on my feet, before I went to bed. It does seem to stop the water leaking out of my skin.
This picture shows my left hand.
I damaged it badly in a fall, where I took the back off on the edge of a glass door. But with some glue from the Royal London and some TLC from the practice nurse, there are no scars. Surely, it shouldn’t mend that well.
As my ancestors include both Jews and Huguenots, did all those centuries in poor living conditions ghetto-harden my skin?
I hate mysteries and I suspect some of my questions could be answered by an experienced dermatologist.
The Anonymous Widower 