Historic Go-Ahead For Malaria Vaccine To Protect African Children
The title of this post, is the same as that of this article on the BBC.
This is the first paragraph.
Children across much of Africa are to be vaccinated against malaria in a historic moment in the fight against the deadly disease.
The vaccine has been developed by GSK, who have their headquarters on the Golden Mile in Brentford.
The vaccine is called RTS,S and is described like this in the first paragraph of its Wikipedia entry.
RTS,S/AS01 (trade name Mosquirix) is a recombinant protein-based malaria vaccine.
Approved for use by European regulators in July 2015, it is the world’s first licensed malaria vaccine and also the first vaccine licensed for use against a human parasitic disease of any kind. The RTS,S vaccine was conceived of and created in the late 1980s by scientists working at SmithKline Beecham Biologicals (now GlaxoSmithKline Vaccines) laboratories in Belgium. The vaccine was further developed through a collaboration between GSK and the Walter Reed Army Institute of Research and has been funded in part by the PATH Malaria Vaccine Initiative and the Bill and Melinda Gates Foundation. Its efficacy ranges from 26 to 50% in infants and young children. On 23 October 2015, the World Health Organization’s Strategic Advisory Group of Experts on Immunization (SAGE) and the Malaria Policy Advisory Committee (MPAC) jointly recommended a pilot implementation of the vaccine in Africa.
When you consider how fast the Covid-19 vaccines were developed, this might appear to have taken a long time to be developed. But then as Wikipedia states, “this is the first vaccine licensed for use against a human parasitic disease of any kind.”
I can’t describe this as anything other than good news.
Life After Pancreatic Cancer
The London Marathon always throws up human stories.
This one from the Argus, which is entitled Youngest London Marathon Runner Raising Funds For Medics Who Saved Her Life, is one of the best I can remember.
These are the first two paragraphs.
The youngest runner in the London Marathon is undertaking the challenge to raise money for the medics who saved her life by carrying out surgery to remove a tumour from her gut the size of a large grapefruit.
Lucy Harvey, from Poole, Dorset, was admitted to Poole Hospital in January 2019 with appendicitis, but the pre-op scans identified a mass on her pancreas.
This story has really touched me.
- My son died at 37 from pancreatic cancer.
- His daughter, who is now eighteen, was born with a congenital hernia of the diaphragm and was saved by heroic surgery in the Royal London Hospital by Vanessa Wright.
- I support pancreatic cancer research at Liverpool University, where I met my late wife in the 1960s.
- I raised a little bit of money, for the pancreatic cancer study I talk about in There’s More To Liverpool Than Football And The Beatles!.
My granddaughter now lives a reasonably normal life!
Has Ciprofloxacin Attacked My Tendon?
After my gallstone operation, the hospital gave me a week’s Ciprofloxacin, which is an antibiotic, to take.
I took one tablet on Thursday evening and another on Friday morning. But as I returned from shopping at the Angel, it felt like I had a splinter in the heel of my left foot.
The pain was so bad I could hardly walk this morning.
I have had plantar fasciitis in the past in my left foot, and as someone, who has spent a working life looking for connections in databases, I wondered if the Ciprofloxacin had anything to do with it.
So I looked up the data sheet on MedLinePlus, which is a trusted site, from the US Library of Medicine.
The data sheet starts with this Important Warning.
This is the first paragraph of the warning.
Taking ciprofloxacin increases the risk that you will develop tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle) during your treatment or for up to several months afterward. These problems may affect tendons in your shoulder, your hand, the back of your ankle, or in other parts of your body. Tendinitis or tendon rupture may happen to people of any age, but the risk is highest in people over 60 years of age. Tell your doctor if you have or have ever had a kidney, heart, or lung transplant; kidney disease; a joint or tendon disorder such as rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function); or if you participate in regular physical activity. Tell your doctor and pharmacist if you are taking oral or injectable steroids such as dexamethasone, methylprednisolone (Medrol), or prednisone (Rayos). If you experience any of the following symptoms of tendinitis, stop taking ciprofloxacin, rest, and call your doctor immediately: pain, swelling, tenderness, stiffness, or difficulty in moving a muscle. If you experience any of the following symptoms of tendon rupture, stop taking ciprofloxacin and get emergency medical treatment: hearing or feeling a snap or pop in a tendon area, bruising after an injury to a tendon area, or inability to move or to bear weight on an affected area.
After reading that, I decided the best thing to do was to call a doctor, so I dialled 111 and within three hours I was seeing a young local doctor in his surgery.
He decided to be prudent and changed the antibiotics.
I have since found out from this page on celiac.com, that not all Ciprofloxacin is gluten-free. Mine was from a company called Torrent.
Covid: Merck’s Antiviral Pill Molnupiravir Slashes Chances Of Illness And Death
The title of this post, is the same as that of this article on The Times.
The title almost sounds to go to be true, but on reading the article, that seems to be even better.
- Halves the chance of going to hospital.
- Slashes chance of death.
Xi Jinping was said to be unavailable for comment.
People With Coeliac Disease Are At Higher Risk For Cataracts
The title of this post is the same as that of this page on Ocli Vision.
This is a paragraph from the article.
In a recent study published by the American Journal of Epidemiology, researchers found that people who suffer from celiac disease are at a much higher risk of developing cataracts than those who are not diagnosed with the disease.
On Monday, Boots identified that my cataracts had got worse and signed me up to a private hospital that could do them free on the NHS.
It was an offer I couldn’t refuse.
Prioritising Patients
Homerton hospital is hoping to remove my gallstones on Thursday by endoscopy, so it’s just a fairly small procedure.
I do wonder if there is a shortage of nurses, doctors and other staff at the hospital caused by either the Covids or the fuel crisis, if some operations will be cancelled.
At no time, in the diagnostic process was I asked if I was in pain. Which I am not!
Surely, in the Age of Covid-19, where there is great uncertainty about predicting hospital capacity just a few weeks in the future, I should have been asked a few questions, so that urgent cases could be given priority if necessary.
As they must have been there for a few months causing me no trouble, surely a few extra weeks won’t make much difference to me.
How Nicki Minaj And Swollen Testicles Became Part Of a UK Coronavirus Briefing
The title of this post, is the same as that of this article on the BBC.
I do like this comment from Sajid Javid on Sky News, from the BBC report.
People that are in the public eye whether they are a celebrity or a politician or whoever they are should be very careful with their language and certainly shouldn’t be spreading untruths.
I had never heard of Nicki Minaj before and I don’t think I want to hear any of her future pronouncements.
I’m Glad I’m Getting Pfizer As My Booster
In Hay Fever, Coeliac Disease And The AstraZeneca Covid-19 Vaccine, I summarised the battle going on in my body over the last few months, between hay fever and the AstraZeneca vaccine.
I wonder what my strong immune system will make of the Pfizer vaccine. I must admit, I’m tempted to just continue with my gluten-free diet and let my immune system sort out the squabble on its own!
Increased Risk Of Atrial Fibrillation In Patients With Coeliac Disease: A Nationwide Cohort Study
I was looking for something else and found this medical paper on the web site of Professor Joe West at Nottingham University.
As I am coeliac, have atrial fibrillation and had a severe stroke from which have made a good recovery. I thought I would post the link, so that others might read what is said.
If my GP or myself had known of the link, my life would probably have been very different.
The Diagnosis Of My Gallstones
I arrived at Homerton hospital as instructed today for the endoscopy.
Strangely, it was C’s birthday.
The procedure would involve passing an ultrasound probe down my throat and through my stomach to take an ultrasound image of the lump close to my liver.
I’d had two endoscopies before in the late 1990s at Addenbrookes to check for coeliac disease. One was a normal one, but in the second, I was also providing a sample of fluid for a research project at Cambridge University.
I seem to remember at Addenbrookes, I had been instructed to turn up in something like a tee-shirt and shorts, which is what I did. In this case, I took my shirt off and put a hospital gown over my cord trousers.
As I’d had the two endoscopies at Addenbrookes without a sedative, I suggested strongly, that they do the investigation without one this time as well.
The doctor, who was of an age to be very experienced, said he was up for it and we went for it without a sedative.
There was two big differences to the procedure at Addenbrookes.
- There were more staff, than Addenbrooke’s doctor and a technician.
- They were fully gowned up, as opposed to normal clothes.
But, then I got the expression at Addenbrooke’s they were aiming for speed and they were only confirming their earlier diagnosis of coeliac disease. that had been made by a genetic test.
Everything this time, went without a hitch.
- I was laying on my left side.
- I had oxygen tubes up my nose.
- With my right hand I can feel the probe in my stomach.
- To calm me down, a nurse was stroking my beard.
After not a long time, everything was done and I was walked back to recovery area.
Within half an hour, I was informed by the second doctor, that I had got gallstones and they would be taken out by endoscopy on September the 30th. Later they will take out my gall bladder by surgery.
I got the impression, it was the first time, that he’d seen this procedure without a sedative, as he described me as the Star-Of-The-Day. But then I’m a London Mongrel, with more survival genes than a garden full of Japanese knotweed.
I went home the way I came – On the bus!
After Effects
The only after effects were that the air in the theatre had dried me out and my left left arm hurt because I’d been lying on it.
So I vowed to drink a lot of fluids before the operation and do something to improve the strength of my damaged left arm.
The Anonymous Widower 