What Are Gail’s Like For Gluten-Free Food
As a coeliac, I just had to ask this question of Google AI and I choose Gail’s as my first test.
This was the answer.
Gail’s offers a standout, award-winning Gluten-Free Sourdough, made in a separate facility for purity, but for other items, cross-contamination is a risk, as they use shared equipment and ingredients. While they have gluten-free salads, flourless cakes, and sometimes other specials, customer experiences vary widely, with some finding staff knowledgeable and careful, while others report poor communication and lack of safe options for severe allergies like Coeliac disease, so always check ingredients and ask staff about specific items.
I think I’ll stay clear.
Are There People, Who Have Very Leaky Skin And Consequently Lose A lot Of Fluids And Have To Drink A Lot. Do Some Become Alcoholics?
I’m actually asking this question for my paternal grandfather, who died on the 25 Jun 1929.
- I obviously never met him.
- My father told me he was a chronic alcoholic.
- My father was upset about his father’s drinking and did his utmost to ensure I didn’t follow his father’s example.
- At no time in my life, have I been drunk day after day, like my paternal grandfather.
- My father set me an excellent example on drinking and I tried to follow his lead.
The question in the title of this post, is based on a composite person of myself and my paternal grandfather.
- In My Strange Skin, I describe the unusual properties of my skin, which often causes medical staff to have a good laugh.
- My previous excellent GP would always take my blood and, never needed a plaster and always had a big smile on his face afterwards.
- I am coeliac and I am fairly certain my father was, but was my paternal grandfather?
I asked Google AI the question in the title of this post and received this AI Overview.
While people generally lose some fluid through normal sweating, there are specific medical conditions that cause excessive fluid loss through the skin, primarily genetic disorders affecting the skin’s barrier function.
One prominent example is Netherton Syndrome, a rare genetic condition that results in a defective skin barrier . People with this condition experience:
- Excessive Trans-Epidermal Water Loss (TEWL): Their skin loses moisture much faster than a healthy person’s skin.
- Dehydration Risk: This requires them to constantly monitor hydration levels and drink plenty of fluids to compensate for the continuous loss.
- Another condition is epidermolysis bullosa (EB), a group of genetic diseases that make the skin very fragile and blister easily. The open wounds and blisters also lead to significant fluid loss, increasing the risk of dehydration and infection.
Note that my skin doesn’t have open wounds and blisters and generally heals well and quickly if I cut myself. My late wife would compliment me on my skin and say it was very much like that of our son, who died of pancreatic cancer.
The second part of the question—whether these individuals become alcoholics as a consequence of their condition—is more complex. There is no evidence in medical literature or research to suggest a direct causal link between having a “leaky skin” condition (which necessitates high fluid intake) and the development of alcoholism.
- Fluid management vs. alcohol consumption: Individuals with these conditions need to consume water, milk, or specific electrolyte-balancing fluids.Alcohol has a diuretic effect, meaning it would actually worsen dehydration and be counterproductive to their necessary fluid management.
- Risk factors for alcoholism: Alcoholism is a complex condition influenced by a combination of genetic, psychological, social, and environmental factors, not by the physiological need to consume large volumes of non-alcoholic fluids.
In summary, certain conditions do cause significant fluid loss through the skin requiring high fluid intake, but this physiological need is managed with appropriate hydration (water, electrolytes), and does not lead to alcoholism.
I will now use, what intelligence I have and my observations of my own body to build on these results.
I Have Very Dry Eyes
I had my first eye test in a shed in a friend’s back garden. But the guy who did it, had been the Senior Eye Surgeon in Ipswich Hospital, so he had practiced at a high level and had a lot of experience.
- During the tests, he remarked to me, that I had the driest eyes he’d ever encountered.
- Afterwards, I got bought the glasses from Boots in Ipswich.
- They were fine and served me well for a number of years.
- A few years later, I was involved in a research project at Moorfields Eye Hospital, where members of the public gave their opinion on new eye testing machines that the NHS might use.
- Moorfields said my eyes were indeed very dry.
- The last professional to comment on my eyes was an opthalmist in Vision Express, who suggested that I bathe my eyes in clean, hot water every morning.
- A couple of days later I saw my GP on another matter and he gave the same advice.
My eyes have been a lot more comfortable since.I also have not had to go to a hospital to have a wayward fly taken out of my eyes, which must have happened perhaps four or five times before.
Are Very Dry Eyes A Sign Of Netherton Syndrome?
I asked Google AI, this question and received this answer.
Yes, very dry eyes can be an associated sign or complication of Netherton Syndrome (NS) and other forms of ichthyosis. The underlying skin barrier defect in NS can lead to various eye problems.
- Ectropion: In some cases, the chronic skin inflammation and tightness can cause ectropion, where the eyelids evert (turn outwards) and do not close properly. This prevents the eyelids from adequately covering and protecting the eyeballs, leading to severe exposure and dryness.
- Ichthyosis and Meibomian Gland Dysfunction: Netherton syndrome is a type of ichthyosis, which is characterized by dry, scaly skin. Patients with ichthyosis often have meibomian gland dysfunction (MGD), where the glands that produce the oily layer of the tear film don’t function correctly. This results in the tear film evaporating too quickly, causing evaporative dry eye.
- Corneal Complications: Chronic dry eye can lead to more severe issues like keratitis (inflammation of the cornea) or punctate epithelial erosions, which are painful and can affect eyesight.
It looks like Google AI is thinking in the right direction.
Are Very Dry Eyes A Sign Of Excessive Trans-Epidermal Water Loss?
I asked Google AI, this question and received this answer.
Yes, very dry eyes are associated with increased trans-epidermal water loss (TEWL) from the ocular surface. Studies have shown that individuals with dry eye disease (DED) have significantly higher ocular TEWL values compared to healthy individuals.
- Tear Evaporation: TEWL from the ocular area is used as a measure of tear evaporation. Excessive tear evaporation is one of the two main causes of DED and leads to a condition called evaporative dry eye (EDE).
- Compromised Barrier: The tear film has a protective lipid (oil) layer that acts as a barrier to prevent excessive evaporation of the aqueous (water) layer of the tear film. A compromised or deficient lipid layer, often caused by meibomian gland dysfunction, results in increased tear evaporation/TEWL.
- Aqueous-Deficient Dry Eye: Even in cases of aqueous-deficient dry eye (ADDE), where the primary problem is low tear production, patients can still experience increased tear evaporation and higher TEWL, indicating a complex overlap between the two main types of DED.
- Ocular Surface Inflammation: Excessive tear evaporation leads to tear hyperosmolarity (increased salt concentration), which is a key factor in causing inflammation and damage to the ocular surface, contributing to the symptoms of very dry eyes.
Are Very Dry Eyes A Sign Of Epidermolysis Bullosa
I didn’t ask Google AI, as it was obvious, when I looked at the pictures on the Internet, that I hadn’t got epidermolysis bullosa.
A Picture Is Worth A Thousand Words
Looking at the pictures of the various causes of dry eye, I came to the conclusion meibomian gland dysfunction could be the cause of my very dry eyes.
Can Meibomian Gland Dysfunction Cause Very Dry Eyes?
I asked Google AI, this question and received this answer.
- Tear Film Breakdown: When glands are blocked (MGD), they produce poor quality or insufficient oil, causing the tear film to break down rapidly.
- Evaporation: Without enough oil, tears evaporate too fast, leaving the eye’s surface exposed, dry, and irritated.
- Gritty, itchy, or burning sensation
- Redness and inflammation
- Watery eyes (paradoxically, due to instability)
- Sticky eyelids or discharge, especially in the morning
- Blurred vision, particularly at the end of the day
If President Maduro Is Found Guilty Of The United States Charges Will He Face The Death Penalty?
I asked Google AI the question in the title of this post and received this answer.
Nicolás Maduro has been indicted on several charges in a U.S. federal court, primarily in the Southern District of New York. The potential penalties for these charges are:
- Narco-terrorism conspiracy: This charge has a mandatory minimum prison sentence of 20 years and a maximum of life in prison.
- Cocaine importation conspiracy: This charge carries a mandatory minimum sentence of 10 years and a maximum of life in prison.
- Weapons charges (using and possessing machine guns and destructive devices in furtherance of the conspiracies): These charges carry a mandatory minimum sentence of 30 years and a maximum of life in prison.
The maximum penalty for all charges combined is life imprisonment in a U.S. federal prison, a sentence that has been described as a “de facto life sentence” in the media. The U.S. Attorney General has stated that the goal is for him to face justice in a U.S. court and, if convicted, he could spend the rest of his life behind bars.
Will this be enough for Trump?
Who knows?
But The Lady On The Train may have a say.
Could Artificial Intelligent Judge Cases Without A Jury?
I just had to ask Google AI this question and received this answer.
Artificial intelligence is not currently used to judge cases or issue final verdicts without human oversight in any major legal system, and legal experts believe a full replacement is unlikely in the foreseeable future. The complex nature of law requires human qualities like empathy, moral judgment, and the ability to assess nuance and credibility, which AI currently lacks.
The current role of AI in the judiciary is primarily used as a tool to assist human judges and lawyers, not replace them.
Could Artificial Intelligent Perform Sentencing In Cases?
I just had to ask Google AI this second question and received this answer.
While artificial intelligence (AI) is already used in various legal processes, it cannot perform actual sentencing in legal cases in a legally binding capacity. Legal systems currently maintain that judicial discretion and the final decision-making authority must rest with a human judge to ensure accountability, due process, and fairness.
Does Artificial Intelligence Support A Reduced Role For Juries In Legal Cases?
I just had to ask Google AI this third question and received this answer.
Artificial intelligence is currently being used to support, not replace, human decision-makers in the legal system, with experts highlighting the need for human judgment, empathy, and accountability in jury trials. The debate over AI’s potential to reduce the role of juries is ongoing, with arguments both for and against.
Conclusion
In all these questions, artificial intelligent didn’t appear to act above its station.
Could Doncaster Sheffield Airport Become A Hydrogen Airport?
I asked Google AI, what is the current status of Doncaster Sheffield Airport and received this reply.
Doncaster Sheffield Airport (DSA) is currently in a state of active, public-funded redevelopment after closing in late 2022 due to financial issues, with plans to reopen for passenger flights by late 2027 or 2028, following significant funding (around £160m) secured by the South Yorkshire Mayoral Combined Authority (SYMCA) for the City of Doncaster Council to take over operations and rebuild commercial viability, with freight and general aviation potentially returning sooner.
This Google Map shows the location of the airport.
Note.
- The distinctive mouth of the River Humber can be picked out towards the North-East corner of the map.
- Hull and Grimsby sit in the mouth of the Humber.
- The red arrow indicates Doncaster Sheffield Airport.
- Leeds is in the North-West corner of the map.
- The towns and city of Doncaster, Rotherham and Sheffield can be picked out to the West of the airport.
This second Google Map shows a close-up of the airport.
On my visit to NASA in the 1980s, where an Artemis system was used to project manage the turnround of the Space Shuttle, I was asked questions by one of NASA’s support people about RAF Finningley. Nothing too technical, but things like what is Doncaster like.
When I asked why, they said there’s a high chance that a Space Shuttle could land at RAF Finningley, as it has one of the best runways for a very heavy aircraft in Europe.
Looking at the runway, it is a long and wide runway that was built for heavy RAF nuclear bombers like Valiants, Victors and Vulcans.
I believe that we will eventually see hydrogen- and/or nuclear-powered airliners flying very long routes across the globe, just as a nuclear-powered example, attempted to do in the first episode of the TV series Thunderbirds, which was called Trapped in the Sky and has this Wikipedia entry.
Just as the Space Shuttle did, these airliners and their air-cargo siblings will need a large runway.
Doncaster Sheffield Airport already has such a runway.
These hydrogen- and nuclear-powered aircraft will make Airbus A 380s look small and will need runways like the one at Finningley.
But I don’t think we’ll ever see nuclear-powered aircraft in the near future, so the aircraft will likely be hydrogen.
Other things in favour of making Doncaster Sheffield Airport, an airport for long range hydrogen aircraft include.
- The airport is close to the massive hydrogen production and storage facilities being developed on Humberside at Aldbrough and Rough.
- The airport could be connected to the Sheffield Supertram.
- The airport could be connected to the trains at Doncaster station, which has 173 express trains per day to all over the country.
- The airport would fit well with my thoughts on hydrogen-powered coaches, that I wrote about inFirstGroup Adds Leeds-based J&B Travel To Growing Coach Portfolio
- The airport might even be able to accept the next generation of supersonic aircraft.
- The airport could certainly accept the largest hydrogen-powered cargo aircraft.
- The Airport isn’t far from Doncaster iPort railfreight terminal.
Did I read too much science fiction?
I have some further thoughts.
Do Electric Aircraft Have A Future?
I asked Google AI this question and received this answer.
Yes, electric aircraft absolutely have a future, especially for short-haul, regional, and urban air mobility (UAM), promising quieter, zero-emission flights, but battery limitations mean long-haul flights will rely more on hydrogen-electric or Sustainable Aviation Fuels (SAF) for the foreseeable future. Expect to see battery-electric planes for shorter trips by the late 2020s, while hybrid or hydrogen solutions tackle longer distances, with a significant shift towards alternative propulsion by 2050.
That doesn’t seem very promising, so I asked Google AI what range can be elected from electric aircraft by 2035 and received this answer.
By 2035, fully electric aircraft ranges are expected to be around 200-400 km (125-250 miles) for small commuter planes, while hybrid-electric models could reach 800-1,000 km (500-620 miles), focusing on short-haul routes due to battery limitations; larger, long-range electric flight remains decades away, with hydrogen propulsion targeting 1,000-2,000 km ranges for that timeframe.
Note.
- I doubt that many prospective passengers would want to use small commuter planes for up to 250 miles from Doncaster Sheffield airport with hundreds of express trains per day going all over the UK mainland from Doncaster station.
- But Belfast City (212 miles), Dublin (215 miles) and Ostend (227 miles), Ronaldsway on the Isle of Man (154 miles) and Rotterdam(251 miles) and Schipol 340 miles) may be another matter, as there is water to cross.
It looks like it will be after 2035 before zero-carbon aircraft will be travelling further than 620 miles.
My bets would be on these aircraft being hydrogen hybrid aircraft.
What Will The Range Of Hydrogen-Powered Aircraft In 2040?
I asked Google AI this question and received this answer.
By 2040, hydrogen-powered commercial aircraft are projected to have a range that covers short- to medium-haul flights, likely up to 7,000 kilometers (approximately 3,780 nautical miles), with some models potentially achieving longer ranges as technology and infrastructure mature.
The range of these aircraft will vary depending on the specific technology used (hydrogen fuel cells versus hydrogen combustion in modified gas turbines) and aircraft size.
It looks like we’ll be getting there.
This Wikipedia entry is a list of large aircraft and there are some very large aircraft, like the Antonov An-225, which was destroyed in the Ukraine War.
A future long-range hydrogen-powered airline must be able to match the range of current aircraft that will need to be replaced.
I asked Google AI what airliner has the longest range and received this reply.
The longest-range airliner in service is the Airbus A350-900ULR (Ultra Long Range), specifically configured for airlines like Singapore Airlines to fly extremely long distances, reaching around 9,700 nautical miles (18,000 km) for routes like Singapore to New York. While the A350-900ULR holds records for current operations, the upcoming Boeing 777-8X aims to compete, and the Boeing 777-200LR was previously known for its exceptional range.
I believe that based on the technology of current successful aircraft, that an aircraft could be built, that would be able to have the required range and payload to be economic, with the first version probably being a high-capacity cargo version.
What Would An Ultra Long Range Hydrogen-Powered Airliner Look Like?
Whatever the aircraft looks like it will need to be powered. Rolls-Royce, appear to be destining a future turbofan for aircraft called the Ultrafan, which has this Wikipedia entry.
I asked Google AI, if Rolls-Royce will produce an Ultrafan for hydrogen and received this answer.
Rolls-Royce is actively developing the UltraFan architecture to be compatible with hydrogen fuel in the future, but the current UltraFan demonstrator runs on Sustainable Aviation Fuel (SAF). The company has a research program dedicated to developing hydrogen-powered engines for future aircraft, aiming for entry into service in the mid-2030s.
I asked Google AI, if Rolls-Royce have had major difficulties converting engines to hydrogen and received this answer.
Rolls-Royce has not encountered insurmountable difficulties but faces significant engineering and logistical challenges in converting engines to run on hydrogen. The company has made substantial progress in testing both stationary and aero engines using pure hydrogen, confirming its technical feasibility.
Given the company’s success in developing engines in the past, like the R Type, Merlin, RB 211, Pegasus, Trent, mtu 4000 and others, I suspect there’s a high chance of a successful hydrogen-powered Ultrafan.
If you look at a history of large passenger and cargo aircraft over the last sixty years, there has been a lot of the following.
- Conversion of one type of aircraft to a totally different type.
- Fitting new engines to a particular type.
- Fitting new avionics to a particular type.
Examples include.
- Fitting new CFM-56 engines to DC-8s.
- The first two Nimrods were converted from unsold Comet 4Cs.
- Converting Victor bombers to RAF tanker aircraft.
- Converting BA Tristars to RAF tanker aircraft.
- Converting DC-8s to cargo aircraft.
- Airbus converted five Airbus A 300-600 into Belugas, which have this Wikipedia entry.
- Airbus converted six Airbus A 330-200F into BelugaXLs, which have this Wikipedia entry.
- Converting two Boeing-747s to carry Space Shuttles ; one from American Airlines and one from Japan Airlines, which have this Wikipedia entry.
Note.
- Most of these examples have been successful.
- The last three examples have been very successful.
- Most of these applications do not have a human cargo.
This picture shows an Emirates Air Lines’s Airbus A 380 on finals at Heathrow.
Note.
- The aircraft was landing on Runway 27 L.
- The four engines and the vertical oval cross-section of the fuselage are clearly visible.
- The Wikipedia entry for the Airbus A 380 shows two floors across the fuselage; the upper floor with eight seats in 2-4-2 and the lower floor with ten seats in 3-4-3, and a pair of LD3 cargo containers in the basement.
I’d be interested to know, how much hydrogen could be put in the basement and how far it could take the plane with a full load of passengers!
This link to the Wikipedia entry, shows the cross section in detail.
Note
I wouldn’t be surprised that the first application of large hydrogen aircraft will be for cargo and it could be an Airbus Beluga or perhaps an Airbus A 380 freighter?
The BYD Buses On Route 141 Appear To Be Dehydrating Me
I took these pictures on one of the new BYD electric buses on route 141 these morning, as it ran between the Moorfields Hospital and the Balls Pond Road stops.
Note.
- There appears to be something wrong with the display, which says “Bus Terminates Here. Please Take Your Belongings With You”
- But it didn’t terminate.
- I’ve noticed these displays have got stuck like this before on BYD buses.
- The display didn’t move during the whole journey.
- Although, the clock seemed to keep almost accurate time.
- I just wonder if the bus is running out of electricity, so the driver or the computer has switched off things like the air-conditioning and the display.
And then after I’d been home for about ten-fifteen minutes, I started to get terrible pins and needles in my right arm.
It was so bad, that I called 111. Luckily it looked like it was nothing serious.
I do have a very leaky skin and I felt I might be dehydrated.
So I asked Google AI if “dehydration causes pins and needles” and received this answer.
Yes, dehydration can cause pins and needles (tingling sensations) because it disrupts the body’s electrolyte balance (like sodium, potassium, calcium), which are crucial for proper nerve and muscle function, leading to impaired nerve signals and tingling, often in hands and feet, especially after weating or intense activity.
As a precaution, I drunk three bottles of low-alcohol Ghost Ship beer and felt a lot better.
I am certain in future, I will only go in a Chinese electric bus, if I’m sure is been fully charged.
Google AI Is Using This Blog
This is a screen-shot from Google.
I had asked Google AI this question “Are Centrica going to provide bunkering services for low carbon shipping?”
Google AI gave me this answer.
Yes, Centrica is actively exploring and planning to provide bunkering services for low-carbon fuels, particularly LNG, with future potential for hydrogen and ammonia at its Isle of Grain terminal, positioning itself as a key player in the energy transition for shipping.
Key Developments & Plans:
- Isle of Grain Terminal: Centrica’s acquisition and development of the Grain LNG terminal is central to this strategy, with plans to expand its capabilities for bunkering various low-carbon fuels.
- Low-Carbon Fuels Focus: While currently handling LNG, Centrica sees future opportunities for hydrogen and ammonia bunkering at the terminal, aligning with the maritime sector’s shift away from heavy fuel oil.
- Strategic Investment: Centrica views LNG as a crucial transition fuel and is investing in infrastructure to support its role in energy security and decarbonization, including for shipping.
- Bio-LNG Involvement: Through its stake in Gasrec, Centrica is also supporting renewable LNG for road transport, indicating broader interest in sustainable gas fuels.
US Government Sends Stop Work Order To All Offshore Wind Projects Under Construction
The title of this post, is the same as that of this article on offshoreWIND.biz.
This is the sub-heading.
The US Department of Interior has paused the leases and suspended construction at all large-scale offshore wind projects currently under construction in the United States, citing ”national security risks identified by the Department of War in recently completed classified reports.”
The wind farms named are.
- Coastal Virginia Offshore Wind-Commercial – 2,600 GW
- Empire Wind 1 – 810 MW
- Revolution Wind – 704 MW
- Sunrise Wind – 924 MW
- Vineyard Wind 1 – 806 MW
Note.
- These five wind farms total 5,844 MW or 5.8 GW.
- The Empire Wind development is being led by Equinor, who are Norwegian.
- The Revolution Wind and Sunrise Wind developments are being led by Ørsted, who are Danish.
- The Vineyard Wind development is being led by Iberdrola, who are Spanish and Copenhagen Infrastructure Partners, who are Danish.
- Coastal Virginia Offshore Wind project uses 176 Siemens Gamesa SG 14-222 DD (Direct Drive) offshore wind turbines.
- Empire 1 Wind is using Vestas V236-15MW offshore wind turbines.
- Revolution Wind is using 65 Siemens Gamesa SG 11.0-200 DD offshore wind turbines.
- Sunrise Wind is using Siemens Gamesa wind turbines, specifically their 8.0 MW models (SG 8.0-167).
- Vineyard 1 Wind is using General Electric (GE) Haliade-X 13 MW offshore wind turbines.
- Some of the components for the Siemens wind turbines will be manufactured in Virginia.
- Coastal Virginia Offshore Wind has a budget of $11.2-3 billion.
- Empire 1 Wind has a budget of $5 billion.
- Resolution Wind has a budget of $4 billion.
- Sunrise Wind has a budget of $5.3 billion.
- Vineyard 1 Wind has a budget of $4 billion.
There will only be one winner in this new round of the ongoing spat between Trump and the wind industry, that he hates so much – the 1.3 million active lawyers in the United States,which is a figure from according to Google AI.
Can Toddlers Get Uncomplicated Pancolonic Diverticular Disease?
I am asking this question, as I do wonder, if I’ve had the disease for many years, as I don’t feel any different now, to how I felt at 18, 30 or 50.
In my first couple of years of life, I was also a bad bed-wetter.
My mother cured me of this, by putting me in a small bed next to her’s and then getting me out of bed every time I woke. In the end her persistence paid off.
Since I’ve been diagnosed with uncomplicated pancolonic diverticular disease, I am certainly drinking a lot of fluids and gooing to the toilet a lot.
Although thankfully, I am not wetting the bed.
But, I do always sleep close to a toilet.
So I asked Google AI the question in the title of this post and received this answer in the form of this peer-reviewed paper, which was entitled Congenital Cecal Diverticulitis In A Pediatric Patient.
This is the abstract.
Diverticulitis in the pediatric population is a very rare cause of abdominal pain. When present in the cecum or ascending colon, it is often incorrectly diagnosed preoperatively as acute appendicitis. This is especially true in Western countries where right-sided diverticulitis is less common. Here we detail a case of a pediatric patient with complicated congenital cecal diverticulitis and review the literature on pertinent management. An extensive work up with imaging and endoscopy was completed and definitive surgical treatment with diverticulectomy an appendectomy was performed. As the incidence of diverticular disease in younger individuals increases, right sided diverticulitis is worthy of consideration on the differential diagnosis.
Note.
- I don’t remember being in any pain, but I was less than three, as this happened before my sister was born, when I was only 21 months old.
- I remember picking my sister up from hospital in my father’s Y-Type MG.
- My eldest son had appendicitis diagnosed at ten, but they didn’t operate. So was it diverticulitis?
- He wasn’t X-rayed or scanned.
- Doctors always believed I had a disease, they couldn’t identify.
- When I was identified as a coeliac at 50, I thought that was the problem.
But then as my now-retired GP said. “Whatever, I’ve got, doesn’t seem serious!”
Did This Get Lost In The Covids?
In October 2019, I wrote Asthma Carbon Footprint ‘As Big As Eating Meat’ and it made me think, when I just read it.
I would normally follow up a post like this, but I don’t remember doing anything like that.
The Wikipedia entry for the COVID-19 pandemic in England, starts with this paragraph.
The COVID-19 pandemic was first confirmed to have spread to England with two cases among Chinese nationals staying in a hotel in York on 31 January 2020.
It looks to me, that like everybody else in England, I had the Covids on my mind.
Is Respimat A Zero-Carbon Inhaler?
Just to be sure, I asked Google AI, the question in the title of this section and received this reply.
The Respimat soft mist inhaler is considered to have virtually no associated carbon emissions from its operation because it does not contain the high global warming potential (GWP) hydrofluorocarbon (HFC) propellants found in metered-dose inhalers (pMDIs).
While it has a substantially lower carbon footprint than traditional pMDIs, it is not strictly “zero-carbon” when considering its entire life cycle, which includes manufacturing, materials (stainless steel, aluminium, polymers), and end-of-life disposal. These factors contribute a small product carbon footprint (PCF).
According to Google AI, a reusable version is available.
A reusable Respimat device has been introduced, which further reduces the carbon footprint by up to 71% over six months compared to the disposable version because the device itself is kept longer, reducing manufacturing impacts.
Google AI says this about NHS guidance.
Health bodies like the NHS encourage the use of lower-carbon inhalers like the Respimat or dry powder inhalers (DPIs) as part of their net-zero targets, provided they are clinically appropriate for the patient.
But it does seem that Respimat devices are helping to cut global warming.
What Is The Patient Experience Of Respimat?
Google AI gave this answer to my question.
Patient experience with the Respimat inhaler is generally very positive, with high satisfaction for its ease of use, handling, and the “soft mist” it produces, leading to high continuation rates in studies; patients find it easier than many older devices and report good effectiveness, though common side effects like dry mouth, cough, and sore throat can occur.
Key Aspects of Patient Experience
- High Satisfaction: Over 85-90% of patients report being satisfied or very satisfied with the Respimat’s handling and the ease of inhaling the mist.
- Preference Over Other Devices: Many patients prefer Respimat over traditional metered-dose inhalers (pMDIs) or dry powder inhalers (DPIs), finding it easier to use and more effective.
- Soft Mist Technology: Patients appreciate the gentle, slow-moving mist, which helps deliver medication effectively and feels different from a typical puff.
- Good Adherence: High satisfaction often translates to continued use, with physicians reporting high patient adherence and continuation rates after studies end.
- Improved Technique: While initial use might need guidance, pharmacist-led interventions show significant improvements in patients’ inhalation technique over time.
That doesn’t look bad to me!
Could Immunotherapy Drugs Be Delivered By An Inhaler?
We always felt the device could deliver other drugs.
Google AI gave this answer to my question.
Yes, immunotherapy drugs could potentially be delivered by an inhaler, and this approach is a promising area of active research and development, particularly for treating lung cancer and respiratory diseases like asthma.
Rationale and Research
- Targeted Treatment: Inhaled delivery allows for high concentrations of the drug to be delivered directly to the lungs, which is particularly beneficial for treating lung-specific conditions like lung cancer or severe asthma. This localized approach aims to maximize the therapeutic effect where needed.
- Reduced Side Effects: By concentrating the medication in the lungs and minimizing its systemic absorption into the bloodstream, researchers hope to significantly reduce the severe side effects (e.g., systemic toxicity, autoimmune reactions) commonly associated with traditional intravenous or oral administration of some immunotherapies and chemotherapies.
- Patient Convenience: Inhalation is a non-invasive administration route, which is more convenient and comfortable for patients compared to injections or intravenous infusions, potentially allowing for self-administration and improving patient compliance.
The Soft Mist Technology could surely be a help!
Was Osborne Reynolds The Greatest Fluid Dynamicist?
I have to ask Google AI this question, as some of the discussions that led to creation of Respimat, took place in my house at Debach, where Osborne Reynolds had lived.
Google AI gave this answer to my question.
Osborne Reynolds is considered one of the most influential and foundational contributors to the field of fluid dynamics, though naming a single person the “greatest” is subjective. His work fundamentally shaped modern engineering and physics and remains central to the study of fluid flow today.
Key Contributions to Fluid Dynamics
Reynolds’ most significant achievements include:
- The Reynolds Number: He identified a crucial dimensionless parameter (now named the Reynolds number) that determines whether fluid flow is laminar (smooth and orderly) or turbulent (chaotic and eddying). This number is a foundational concept used across all engineering and physical sciences.
- The Theory of Turbulence: In an 1895 paper, he established the standard mathematical framework used in the study of turbulence, introducing what is known as the Reynolds-averaged Navier–Stokes equations.
- Experimental Validation: His elegant, yet simple, dye experiments visually demonstrated the transition between flow regimes, providing clear empirical evidence for his theories.
- Theory of Lubrication: He developed the Reynolds equation in 1886, which still underpins the analysis of hydrodynamic lubrication in modern bearings.
- Heat Transfer and Similitude: His research into heat transfer between solids and fluids led to significant improvements in boiler and condenser designs, and his work on hydraulic similitude enables engineers to use scaled-down models (e.g., in wind tunnels for aircraft design) to predict the performance of full-scale machines.
How Many Good Ideas Did The Covids Delay?
It could be that the roll-out of Respimat for was delayed by the Covids!
But it wouldn’t have been the only idea to have been delayed in that way!
The Anonymous Widower 
