Could Liverpool Develop A Massive Zero-Carbon Data Centre?
There is an article in The Sunday Times today, which is entitled Google Signs Nuclear Deal To Power AI Data Centres.
These are the first three paragraphs of the article.
Google has struck a deal with a nuclear power start-up to provide low-carbon energy for its data centres and AI operations, marking a world-first in the tech industry.
The California-based company said the agreement to buy energy from multiple small modular reactors developed by Kairos Power could help spur a nuclear revival in America.
The first reactor is scheduled to come online in America by 2030, followed by additional deployments through 2035.
I am not against nuclear-powered data centres, but could Liverpool build a massive zero-carbon data centre?
This Google Map shows Liverpool Bay, which is a vast expanse of water that stretches along the North Wales coast to Anglesey and all the way to the Isle of Man.
Note.
- The Isle of Man in the North-West corner.
- Liverpool, Birkenhead and the River Mersey in the South-East corner.
- Anglesey in the South-West corner.
- Blackpool with Morecambe Bay to its North in the North-East corner.
Liverpool Bay could be one of Europe’s zero-carbon energy powerhouses.
Wind Farms In Liverpool Bay
At the present time, these wind farms are producing electricity or planned in Liverpool Bay.
- Barrow – 90 MW – Commissioned in 2006
- Burbo Bank – 90 MW – Commissioned in 2007
- Burbo Bank Extension – 258 MW – Commissioned in 2017
- Gwynt y Môr – 576 MW – Commissioned in 2015
- North Hoyle – 60 MW – Commissioned in 2003
- Ormonde – 150 MW – Commissioned in 2012
- Rhyl Flats – 90 MW – Commissioned in 2009
- Walney – 367 MW – Commissioned in 2010
- Walney Extension – 659 MW – Commissioned in 2018
- West if Duddon Sands – 389 MW – Commissioned in 2014
- Awel y Môr – 500 MW – Planned
- Morecambe – 480 MW – Planned
- Mona – 1500 MW – Planned
- Morgan – 1500 MW – Planned
Note.
- 2509 MW has been commissioned.
- 3980 MW is being planned.
- That is a total of 6489 MW
I suspect more space in Liverpool Bay could be developed with wind farms.
Mersey Tidal Power
The Mersey Tidal Power project has a web site.
If it is built, it will probably be built by the South Korean company; K-Water and use some of the design principles of the Sihwa Lake Tidal Power Station.
It will likely have an output of around 1 GW and take ten years to build.
In the 1970s, I did some project management consultancy for Frederick Snow and Partners, and they showed me their plans for a Severn Barrage.
Their futuristic vision for the Severn Estuary was never built, as the Prime Minister of the time; Harold Wilson, felt coal was the future. See Last Of The Many!
I suspect that the Mersey Tidal Power project will be another variation on a proven theme.
Morecambe Bay Bridge And Tidal Barrage Proposal
In the Wikipedia entry for Morecambe Bay, there is a proposal for a bridge and tidal barrage across the bay, where this is said.
In 2004, a proposal was made to build a bridge across the bay flanked by wind turbines and using tidal power. Proposals from Northern Tidal Power Gateways in 2019 outlined a tidal barrage with a road running along on top.
If the Mersey Tidal Power project is a success, then why wouldn’t one across Morecambe Bay, be one too?
500 MW of zero-carbon tidal power would do nicely!
Nuclear Sites At Calder Hall, Heysham And Wylfa
These three nuclear stations have supplied electricity to the North-West of England.
- Calder Hall was the original Magnox site, which the Wikipedia entry says had a nameplate capacity of 240 MW and was decommissioned in 2003, after running for 47 years.
- Heysham is a powerful site which the Wikipedia entry says has a nameplate capacity of 2452 MW and will be decommissioned in 2028.
- Wylfa is an older, smaller Magnox site which the Wikipedia entry says had a nameplate capacity of 1190MW and was decommissioned in 2015.
As the sites are cleared, I am sure that we’ll see more nuclear power stations built on the sites.
How Much Electricity Does A Data Centre Use?
I found this paragraph in an NESO document.
Regardless of this, if we were to use existing market data and modelling projections, this could point to annual data centre electricity consumptions of between 3.6 TWh in 2020 to as much as 35 TWh by 2050.
Dividing by the hours in a year, indicates that an individual data centre could use between 0.4 and 4 GW of electricity.
Using my rough figures here from wind, tidal and nuclear, I suspect that the power on the Mersey will generate enough power for at least one data centre.
Liverpool Is On The Right Side Of The Country For Cables To North America
Cables will go straight out of Liverpool Bay, pass to the North of Ireland and across the Atlantic to somewhere like Puget Sound.
Liverpool has a superb location for a Transatlantic data centre, that connects to networks on both sides of the pond.
Could Underwater Data Centres Be Developed In Liverpool Bay?
This page on the Microsoft web site is entitled Microsoft Finds Underwater Datacenters Are Reliable, Practical And Use Energy Sustainably
These three paragraphs detail the research.
Earlier this summer, marine specialists reeled up a shipping-container-size datacenter coated in algae, barnacles and sea anemones from the seafloor off Scotland’s Orkney Islands.
The retrieval launched the final phase of a years-long effort that proved the concept of underwater datacenters is feasible, as well as logistically, environmentally and economically practical.
Microsoft’s Project Natick team deployed the Northern Isles datacenter 117 feet deep to the seafloor in spring 2018. For the next two years, team members tested and monitored the performance and reliability of the datacenter’s servers.
I would assume that Microsoft have continued the research, as with something like this you can’t be too careful.
But it would appear, that data centres and their servers could be submerged under the waters of Liverpool Bay.
London And Liverpool Will Be Under Two Hours By Train Within A Year
New Class 807 trains, which will be delivered within a year, will improve the train service between the two cities.
- Train times will be brought to around or even below two hours.
- , The extra trains will allow a second hourly service to be added.
- The extra service will additionally stop at Liverpool South Parkway station, for the airport.
- High Speed Two is claiming one hour and fifty minutes, between London and Liverpool.
Liverpool already has one of the best rail terminals in the North of England, as these pictures show.
With these service improvements, it will have a service to London and the South, that will be second to no other Northern station.
Liverpool Has A Refurbished Partly-Underground Suburban Railway With New Trains
Liverpool’s Metro is one of the best in Europe for a medium-sized city.
The Metro is also expanding with new routes and stations.
These pictures show the new Headbolt Lane station, which is swerved by the UK’s first battery-electric trains.
Liverpool Has Easy Access To Two International Airports
There are two international airports close by; Liverpool John Lennon and Manchester International.
- For Liverpool Airport, it’s a bus from Liverpool South Parkway station or an express bus from Liverpool city centre.
- For Manchester Airport, it’s a train from Lime Street station.
I am fairly sure, that a hydrofoil could connect Liverpool’s Waterfront and the Tidal Barrier to the airport.
North-West England Has A Rich University Tradition
Liverpool, Manchester and the surrounding area has several world-class universities and research establishments.
Some like The Pandemic Institute would be able to find uses for all the computing power and artificial intelligence on offer at a powerful data centre.
Liverpool Is A World City
Liverpool is a World City, where there is plenty of sport, entertainment and things to do.
Conclusion
Liverpool is installing the power infrastructure for a very large data centre, that will be able to handle the world’s largest and most difficult problems.
Gluten And Heart Disease
Type “Gluten And Heart Disease” into Dr. Google and you find two major peer-reviewed studies.
This study is entitled Effects Of A Gluten-Reduced Or Gluten-Free Diet For The Primary Prevention Of Cardiovascular Disease.
These are the authors’ conclusions.
Very low-certainty evidence suggested that it is unclear whether gluten intake is associated with all-cause mortality. Our findings also indicate that low-certainty evidence may show little or no association between gluten intake and cardiovascular mortality and non-fatal myocardial infarction.
There would appear to be no strong link, between gluten and heart disease.
This British study is entitled Long Term Gluten Consumption In Adults Without Celiac Disease And Risk Of Coronary Heart Disease: Prospective Cohort Study.
These were the authors’ conclusions.
In these two large, prospective cohorts, the consumption of foods containing gluten was not significantly associated with risk of coronary heart disease. Although people with and without celiac disease may avoid gluten owing to a symptomatic response to this dietary protein, these findings do not support the promotion of a gluten restricted diet with a goal of reducing coronary heart disease risk. In addition, the avoidance of dietary gluten may result in a low intake of whole grains, which are associated with cardiovascular benefits. The promotion of gluten-free diets for the purpose of coronary heart disease prevention among asymptomatic people without celiac disease should not be recommended.
As before there would appear to be no strong link between gluten and heart disease.
To me, this is the most important sentence.
In addition, the avoidance of dietary gluten may result in a low intake of whole grains, which are associated with cardiovascular benefits.
So can we do something about it?
Enter The First Great Ethiopian Marathon Runner
I used to run a bit (badly) at school and my three heroes were Chris Brasher, Bruce Tulloh and Abebe Bikula.
The Ethiopian; Abebe Bikula was a double Olympic marathon champion.
- In 1960, he won in Rome, running barefoot.
- In 1964, he won in Tokyo, a few days after leaving hospital after having his appendix removed.
Both wins were in world record time.
Since 1964, three Olympic men’s marathons have been won by Ethiopians.
Ethiopian women have also won two gold and one bronze medals since the women’s marathon was inaugurated in 1984.
And then there’s the Kenyans, who’ve won a hatful of marathon medals.
Their competence is generally put down to living at altitude and I wouldn’t disagree with that.
My Experience Of Kenya
Soon after C died, I went on holiday to Kenya.
In one part of the holiday, I was riding horses in the Masai Mara and in the other I was glamping.
The second part was upmarket and one evening the chef approached me to find out more about my gluten-free diet. At breakfast next day, he presented me with a couple of rolls made from a local flour, which was probably something like millet or perhaps, teff from Ethiopia.
I had no adverse reaction. and he said, I could eat like a true African, as Western flour had no place in the local diet.
Conclusion
If we are worried about the lack of whole grains in gluten-free food, then perhaps we should add gluten-free whole grains from East Africa.
As a manager in a Marks and Spencer store, told me that they used Ethiopian flour in their gluten-free breads, I suspect this is already happening.
The Aerosol Tales
When I left Liverpool University in 1968, I was very familiar with the use of products distributed in aerosol cans.
- I had used aerosol shaving cream, although about that time, I acquired my beard.
- I certainly used aerosol deodorant, as did most in the 1960s.
- Aerosol paints were common for covering scuffs and scratches in your car.
- Aerosols were often used to apply sun protection.
- Aerosols containing cream or a non-dairy alternative for culinary use were not unknown.
- Aweosol lubricants were starting to appear.
Although, I went to work for the chemical giant; ICI, at that time, I had no idea how an aerosol and its can worked.
As ICI at the time, ICI were major manufacturers of aerosol propellants, I quickly learned how they worked.
The Wikipedia entry for Aerosol Spray Dispenser gives a lot of history about aerosol cans and their propellants.
The Wikipedia entry for Propellant has this paragraph describing propellants of the last century.
Chlorofluorocarbons (CFCs) were once often used as propellants, but since the Montreal Protocol came into force in 1989, they have been replaced in nearly every country due to the negative effects CFCs have on Earth’s ozone layer. The most common replacements of CFCs are mixtures of volatile hydrocarbons, typically propane, n-butane and isobutane. Dimethyl ether (DME) and methyl ethyl ether are also used. All these have the disadvantage of being flammable. Nitrous oxide and carbon dioxide are also used as propellants to deliver foodstuffs (for example, whipped cream and cooking spray). Medicinal aerosols such as asthma inhalers use hydrofluoroalkanes (HFA): either HFA 134a (1,1,1,2,-tetrafluoroethane) or HFA 227 (1,1,1,2,3,3,3-heptafluoropropane) or combinations of the two. More recently, liquid hydrofluoroolefin (HFO) propellants have become more widely adopted in aerosol systems due to their relatively low vapor pressure, low global warming potential (GWP), and nonflammability.
Note that the whole range of these chemicals, effect the ozone layer.
Rocksavage Works
ICI’s Rocksavage Works, was an integrated chemical plant by the Mersey,.
- It made all types of CFCs for aerosols and other purposes.
- It also made the fire suppressant and extinguisher; Bromochlorodifluoromethane or BCF.
- Alongside BCF, it made the anaesthetic Halothane or as ICI called it Fluothane.
- The plant was a poisonous place with all those bromine, chlorine and fluorine compounds.
- Despite this, the plant had a remarkable safety record.
I had the pleasure of working at the plant and it was where, I had most of my excellent Health and Safety training, from the amazing site foreman; Charlie Akers.
Some of the wisdom he distributed has proved invaluable in aiding my stroke recovery.
I suspect that since the signing of the Montreal Protocol, the plant has changed greatly or has even been closed.
All that appears to be left is the 800 MW gas-fired Rocksavage power station and a Facebook page.
Aerosol Baked Beans
In those days, I worked most of the time in a lab at Runcorn Heath.
One of the labs near to where I generally worked, in the large research complex, was a lab, where new aerosol products were developed and tested.
One of the standard jokes about that lab, was that they were working on aerosol baked beans. They said, they would develop the product, even of they had to eject them from the can one at a time.
Gift Time
One afternoon, the boss of the aerosol development lab came through with a tray of goodies.
On the tray, which was much like a cinema usherette’s ice cream tray of the sixties was a whole host of partly-labeled aerosol cans. Only clues to what the product might be were written on the outside in felt-tip pen.
I grabbed two, one of which was marked something like lubricating oil and the other was just marked hand cream, which I of course gave to my new wife; C.
We were married for nearly forty years and often, when she bought hand cream, she would remark, that it wasn’t of the same standard as the little can I brought home from work.
It appears to me, that one of the world’s top cosmetic companies and ICI were trying to create the world’s best and probably most expensive hand creams.
DMW
Fast-forward nearly twenty years and I was approached by Lloyds Bank about two individuals, who had developed an aerosol valve, that instead of using CFCs or other ozone-depleting chemicals.
- By the exploitation of the nether end of fluid dynamics, the propellant of the aerosol was nothing more harmless than pure nitrogen.
- I formed a company called DMW with the two inventors.
- John Gummer, who at the time was my MP and Environment Minister, knew of the aerosol valve and he took the details to Montreal.
So did a device developed in Suffolk help push through the Montreal Protocol?
Osbourne Reynolds
I also wonder, if we had some supernatural help. At the time, I lived in the family home of Osbourne Reynolds.
- He did a lot of the early work on fluid dynamics.
- He was the first UK Professor of Engineering.
- He was professor of Engineering at Manchester University for nearly forty years.
- The Reynolds number is named after him.
- Remarkably, students are sill taught on the equipment Reynolds designed.
- Reynolds was certainly one of our great Victorian scientists.
This Wikipedia entry gives more details of his remarkable life and work.
After Montreal the aerosol valve was sold to Johnson & Johnson.
DMW continued to develop other products and we had one, who no-one had any idea about how it worked.
So I discussed it with the Reynolds’s expert at Manchester University and he said he had no idea either.
But he was absolutely certain, that Reynolds would have known.
UK Breakthrough Could Slash Emissions From Cement
The title of this post. is the same as that of this article on the BBC.
This is the sub-heading.
Scientists say they’ve found a way to recycle cement from demolished concrete buildings.
These five paragraphs outline, why cement is such an environmental problem.
Cement is the modern world’s most common construction material, but it is also a huge source of planet-warming gas emissions.
That is because of the chemical reactions when you heat limestone to high temperatures by burning fossil fuels.
Recycling cement would massively reduce its carbon footprint. Researchers say that if they switched to electric-powered furnaces, and used renewable energy like wind and solar rather than fossil fuels, that could mean no greenhouse gases would be released at all.
And that would be a big deal. Cement forms the foundation of the modern economy, both literally and metaphorically.
It is what binds the sand and aggregate in concrete together, and concrete is the most widely used material on the planet after water.
If cement was a country, it would be the third biggest source of emissions after China and the US, responsible for 7.5% of human-made CO2.
This article shows how by applying chemical magic to two effectively unrelated processes; the recycling of steel and the recycling of concrete to make new cement, very high rewards are possible.
Cambridge University are calling their new product electric cement.
As large amounts of electricity are used in an arc furnace, to produce the two products
These paragraphs outline the innovative Cambridge process.
Cement is made by heating limestone to up 1600 Celsius in giant kilns powered by fossil fuels.
Those emissions are just the start. The heat is used to drive carbon dioxide from the limestone, leaving a residue of cement.
Add both these sources of pollution together and it is estimated that about a tonne of carbon dioxide is produced for every tonne of cement.
The team of scientists,, has found a neat way to sidestep those emissions.
It exploits the fact that you can reactivate used cement by exposing it to high temperatures again.
The chemistry is well-established, and it has been done at scale in cement kilns.
The breakthrough is to prove it can be done by piggybacking on the heat generated by another heavy industry – steel recycling.
When you recycle steel, you add chemicals that float on the surface of the molten metal to prevent it reacting with the air and creating impurities. This is known as slag.
The Cambridge team spotted the composition of used cement is almost exactly the same as the slag used in electric arc furnaces.
They have been trialling the process at a small-scale electric arc furnace at the Materials Processing Institute in Middlesbrough.
These are my thoughts.
The Only Inputs Are Steel Scrap, Green Electricity And Used Cement
Consider.
- We probably need to increase the percentage of steel scrap we collect.
- Gigawatts of green electricity in a few years, will be available in those places like Port of Ardersier, Port Talbot, Scunthorpe and Teesside, where large amounts of steel will be needed.
- I can envisage large steel users having their own hybrid electric cement/electric arc furnace plants.
- Used cement would be collected and brought to the plants.
- Years ago, I used to live next door to an old World War II airfield. The farmer who owned the airfield, told me, that the concrete was his pension, as when he needed money, he called a company, who crushed it up for aggregate.
I can see a whole new integrated industry being created.
Conclusion
This could be one of the best inventions since sliced bread.
The Problem Of Waste Plastic And Why Pyrolysis Oil Might Just Contain The Answer
The title of this post, is the same as that of this article on the Chemical Engineer.
These three paragraphs introduce the article.
One of the few technologies that can break down unrecyclable post-consumer waste plastic, pyrolysis is fast becoming a potential recycling route for companies trying to reduce their waste output.
The world produces around 450m t/y of plastic, but only 9% is recycled, with most waste ending up in landfill. Pyrolysis, which involves heating the plastic at extremely high temperatures in the absence of oxygen, breaks down the molecules to produce pyrolysis oil or gas. The oil can then be used to develop new products.
George Huber, a professor of chemical engineering at the University of Wisconsin-Madison, is leading a research team that is investigating the chemistry of pyrolysis oil and its use in polyolefin recycling.
This is a quote from George Huber
Waste plastic should be viewed as a resource we can use to make plastics and other chemicals. We should not be landfilling or burning it, we should be reusing the carbon in waste plastics.
I very much agree with what he said.
These are my thoughts.
Pyrolysis
The Wikipedia entry for pyrolysis starts with this paragraph.
The pyrolysis (or devolatilization) process is the thermal decomposition of materials at elevated temperatures, often in an inert atmosphere.
This paragraph describes the technique’s use in the chemical industry.
The process is used heavily in the chemical industry, for example, to produce ethylene, many forms of carbon, and other chemicals from petroleum, coal, and even wood, or to produce coke from coal. It is used also in the conversion of natural gas (primarily methane) into hydrogen gas and solid carbon char, recently introduced on an industrial scale. Aspirational applications of pyrolysis would convert biomass into syngas and biochar, waste plastics back into usable oil, or waste into safely disposable substances.
I came across pyrolysis in my first job after graduating, when I worked at ICI Runcorn.
ICI were trying to make acetylene in a process plant they had bought from BASF. Ethylene was burned in an atmosphere, that didn’t have much oxygen and then quenched in naphtha. This should have produced acetylene , but all it produced was tonnes of black soot, that it spread all over Runcorn.
I shared an office with a guy, who was using a purpose-built instrument to measure acetylene in the off-gas from the burners.
When he discovered that the gas could be in explosive limits, ICI shut the plant down. The Germans didn’t believe this and said, that anyway it was impossible to do the measurement.
ICI gave up on the process and demolished their plant, but sadly the German plant blew up.
I would assume we have progressed with pyrolysis in the intervening fifty years.
University of Wisconsin-Madison
The University of Wisconsin-Madison is a top-ranked American University and is part of my daily life, as the Warfarin, that stops me having another stroke was developed at the University in the 1940s.
Conclusion
The article is a must-read and I feel that my past experience says, that George Huber and his team could be on to something.
I wish them the best of luck.
Application Of Control Engineering Principles To The Calculation Of Pharmaceutical Drug Doses
Today, I was asked by an eminent cardiologist to give my opinion on this scientific paper in the Journal of the American Heart Association, which was entitled Personalized Antihypertensive Treatment Optimization With Smartphone‐Enabled Remote Precision Dosing of Amlodipine During the COVID‐19 Pandemic (PERSONAL‐CovidBP Trial).
This was the background to the study.
The objective of the PERSONAL‐CovidBP (Personalised Electronic Record Supported Optimisation When Alone for Patients With Hypertension: Pilot Study for Remote Medical Management of Hypertension During the COVID‐19 Pandemic) trial was to assess the efficacy and safety of smartphone‐enabled remote precision dosing of amlodipine to control blood pressure (BP) in participants with primary hypertension during the COVID‐19 pandemic.
These were the methods and the results.
This was an open‐label, remote, dose titration trial using daily home self‐monitoring of BP, drug dose, and side effects with linked smartphone app and telemonitoring. Participants aged ≥18 years with uncontrolled hypertension (5–7 day baseline mean ≥135 mm Hg systolic BP or ≥85 mm Hg diastolic BP) received personalized amlodipine dose titration using novel (1, 2, 3, 4, 6, 7, 8, 9 mg) and standard (5 and 10 mg) doses daily over 14 weeks. The primary outcome of the trial was mean change in systolic BP from baseline to end of treatment. A total of 205 participants were enrolled and mean BP fell from 142/87 (systolic BP/diastolic BP) to 131/81 mm Hg (a reduction of 11 (95% CI, 10–12)/7 (95% CI, 6–7) mm Hg, P<0.001). The majority of participants achieved BP control on novel doses (84%); of those participants, 35% were controlled by 1 mg daily. The majority (88%) controlled on novel doses had no peripheral edema. Adherence to BP recording and reported adherence to medication was 84% and 94%, respectively. Patient retention was 96% (196/205). Treatment was well tolerated with no withdrawals from adverse events.
These were the conclusions.
Personalized dose titration with amlodipine was safe, well tolerated, and efficacious in treating primary hypertension. The majority of participants achieved BP control on novel doses, and with personalization of dose there were no trial discontinuations due to drug intolerance. App‐assisted remote clinician dose titration may better balance BP control and adverse effects and help optimize long‐term care.
About Myself
I am a Graduate Control Engineer, who graduated from the University of Liverpool in 1968.
I then worked at ICI in Runcorn for eighteen months, before moving to ICI Plastics Division, because of the untimely death of my father-in-law.
One of my tasks at Welwyn, was to look at control algorithms for chemical plants. For this I often used a PACE 231-R analogue computer.
Note.
- These computers could solve up to a hundred simultaneous differential equations at one time.
- They were programmed by wiring the various amplifiers and potentiometers together to simulate the equations.
- There were only a few transistors in these powerful machines, as all electronics were thermionic valves.
- Two of these machines wired together, were used to calculate the trajectories of the Apollo missions.
They were the unsung heroes of bringing Jim Lovell and Apollo 13 home safely.
Determining Control Algorithms
In a typical problem, I would model the a section of a chemical plant and the control system around it.
This would then lead to recommendations, as to the design and operation of the plant, so that it performed as required.
It could be argued that the body of an animal, is a very complicated integrated chemical plant, with a sophisticated control system.
For instance, if sensors around the body, say you are slightly low on fluids, your brain determines you should have a drink.
Many control loops on a chemical plant are controlled by proportional–integral–derivative controllers, which are commonly known as three-term controllers.
This is the first two paragraphs of the Wikipedia entry for three-term controllers.
A proportional–integral–derivative controller (PID controller or three-term controller) is a control loop mechanism employing feedback that is widely used in industrial control systems and a variety of other applications requiring continuously modulated control. A PID controller continuously calculates an error value
PID systems automatically apply accurate and responsive correction to a control function. An everyday example is the cruise control on a car, where ascending a hill would lower speed if constant engine power were applied. The controller’s PID algorithm restores the measured speed to the desired speed with minimal delay and overshoot by increasing the power output of the engine in a controlled manner.
I wouldn’t be surprised that the app in the smartphone used in the PERSONAL‐CovidBP Trial contained a form of three-term controller.
These are some points about three-term control algorithms.
Changing Of External Factors
One that was the villain in a problem, I dealt with, also affects my body – the weather.
I was asked to look at the problem of a chemical reaction, that overheated in hot weather. But the plant operators solved it by better insulation and ventilation of the plant and the standard three-term controller adjusted itself automatically to the new conditions.
After my stroke, I am on Warfarin for life. I test my own INR with a Roche meter and I have noticed that atmospheric pressure affects my INR. I change my deose accordingly, using a simple algorithm, of my own design.
The More You Test The More Precise The Control
If you take the cruise control example used by Wikipedia, speed is monitored continuously, as I hope, it would be if you were driving yourself.
But obviously, in many systems, where you are using an input with discrete values to control a system, you can’t be as precise as the data you collect.
When my son was dying from pancreatic cancer, he was fitted with a morphine pump, that he could adjust himself to dull the immense pain he was enduring.
- His nerves and his brain ascertained the pain level.
- He then adjusted the morphine level.
- He could get very precise control of his pain, because he was measuring it continuously.
But he was only using simple one-term control (proportional).
Derivative Control Can Be Difficult To Get Right And Can Even Go Unstable
Derivative control is mainly to stop overshoot, but sometimes you will find that it can go unstable, so two-term(proportional+integral) controllers will be used.
How I Control My INR
As I said earlier, I am on Warfarin for life and test my INR with a Roche meter.
The NHS typically tests patients about once every six weeks, which in my opinion as a Control Engineer is too infrequent.
I usually test myself a couple of times a week.
But every so often, I evaluate what daily dose gives me an equilibrium INR level of 2.5.
For the last three years, I have found a dose of 3.75 mg keeps me more or less on 2.5.
- As Warfarin comes in 1, 3, 5 and 10 mg. tablets, I alternate 3.5 and 4 mg.
- Warfarin tablets are easily cut in half using a sharp knife.
- I record INR and dose in a spreadsheet.
I have been doing this now for over ten years.
Is This A Unique Property Of Warfarin?
In this time, I have had five medical procedures, where surgeons were worried, that as I was on Warfarin, I might bleed too much.
For the first, which was to remove a lump from my mouth, the private surgeon wanted to charge extra for an anaesthetist. In the end, I asked what INR he wanted and he said 2.1 should be OK!
- So I reduced the Warfarin level and tested every day.
- I judged it correctly and had an INR of 2.1 on the day of the operation.
- The operation went incredibly well and I went home on public transport.
- The lump turned out to be benign.
- I’ve not had another lump.
After the operation, I increased the Warfarin level and tested every day, until it regained a level of 2.5.
On analysing my doses through the date of the operation, I found that the total amount of Warfarin, I didn’t take to reduce my INR to 2.1, was the same as I took to bring it back up again to 2.5.
Is this a unique property of Warfarin?
Since then I’ve had two cataract operations performed in a private hospital, where the NHS paid. Interestingly, they wouldn’t trust my own INR readings, so I had to get my GP to take the measurement.
I’ve also had gallstones removed by endoscopy at the local Homerton NHS hospital.
- For cases like mine, the hospital hire in a surgeon from the posh Wellington private hospital for one day a week, who brings the specialist tools needed.
- I wrote about this in Goodbye To My Gallstones.
- As it was a more serious procedure, I reduced my INR to a requested 1.0.
Interestingly, I still have my gall bladder, but the surgeon put it on notice to behave.
Conclusion
I would totally agree with the conclusion given in the PERSONAL‐CovidBP Trial.
Personalized dose titration with amlodipine was safe, well tolerated, and efficacious in treating primary hypertension. The majority of participants achieved BP control on novel doses, and with personalization of dose there were no trial discontinuations due to drug intolerance. App‐assisted remote clinician dose titration may better balance BP control and adverse effects and help optimize long‐term care.
I would add some conclusions of my own.
- The app used in the PERSONAL‐CovidBP Trial, seems to have had a good algorithm.
- I suspect the app could also be Internet-based.
These are some general conclusions.
- If you are on Warfarin and have access to a Roche meter, it is possible to lower your INR to the value required by a surgeon for an operation or a procedure.
- Since starting to take Warfarin, I have had four operations or procedures, where others would have had anaesthetic or a sedative.
- In those four operations, I was able to go home on public transport. If I still drove a car, I could have driven home afterwards.
- Private hospitals like to use an anesthetist, as it pumps up the bill.
- Avoiding anaesthesia must save hospitals money.
Well designed apps, based on Control Engineering principles, that help the patient take the best dose of a drug will become more common.
Work Starts On World’s Largest Floating Solar Project, Part of RWE’s OranjeWind
The title of this post, is the same as that of this article on offshoreWIND.biz.
This is the sub-heading.
The Nautical SUNRISE consortium partners have commenced the project whose goal is to facilitate research and development of offshore floating solar systems and its components. The project aims to integrate a 5 MW offshore floating solar system within RWE’s OranjeWind, a wind farm to be built 53 kilometres off the Dutch coast.
These three paragraphs outline the project.
Research and development on the offshore floating solar (OFS) systems and its components of the EUR 8.4 million project, supported by EUR 6.8 million of the Horizon Europe programme, kicked off in December 2023.
The project will enable the large-scale deployment and commercialisation of offshore floating solar systems in the future, both as standalone systems and integrated into offshore wind farms.
The project aims to design, build, and showcase a 5 MW OFS system using the modular solution of the Dutch floating company SolarDuck.
Note.
- It’s only the fourth of March and this is the second floating solar project of the month.
- The first was SolarDuck, Green Arrow Capital And New Developments S.R.L. Sign Collaboration Agreement For A Grid-Scale Offshore Hybrid Wind-Solar Project In Italy.
- I can understand Italy, but surely a solar farm in the Dutch waters of the North Sea, is being at least slightly optimistic.
But the home page of the Oranjewind web site, does have a mission statement of Blueprint For The New Generation Of Offshore Wind Farms.
Under a heading of The Perfect Match, this is said.
RWE’s OranjeWind offshore wind farm will be located 53 kilometers from the Dutch coast. To tackle the challenges of fluctuating power generation from wind and flexible energy demand, RWE has developed a blueprint for the integration of offshore wind farms in the Dutch energy system.
A combination of smart innovations and investments will be used to realise this perfect match between supply and demand.
Under Innovations At OranjeWind, this is said.
In order to realise system integration and accelerate the energy transition, RWE is working together with a number of innovators on new developments in offshore wind farms. The company is realising and testing these innovations in the OranjeWind wind farm.These innovations include offshore floating solar, a subsea lithium-ion battery, LiDAR power forecasting system and a subsea hydro storage power plant off-site.
These technologies have their own sections, which give more information.
- Subsea Pumped Hydro Storage Power Plant (Ocean Grazer)
- Floating Solar (SolarDuck)
- Intelligent Subsea Energy Storage (Verlume)
- LiDAR-based Power Forecasting (ForWind, University of Oldenburg)
The web site also says this about knowledge from OranjeWind.
There is a lot to learn in an innovative project such as OranjeWind. While developing the wind farm, RWE started the OranjeWind Knowledge programme. This programme aims to generate and share knowledge to accelerate the energy transition.
In strong partnerships with TNO and Dutch universities, research is carried out in parallel to the development and operation of OranjeWind. By sharing research results, lessons learned, and relevant in-house expertise, RWE aims to close knowledge gaps and provide valuable insights in key focus areas for system integration. The generated knowledge will become openly available to educational and research institutes, governments and the market.
To ensure the dissemination of knowledge, RWE will actively partner with educational institutions of all levels across the Netherlands. These partnerships allow RWE to share its expertise and provide the future workforce with the knowledge and skills needed to enable the energy transition.
It certainly appears that RWE intends to get as much out of this project as they can.
I don’t think that they can be criticised for that objective.
Binge Drinking And Obesity Behind Bowel Cancer Surge In Under-50s
The title of this post, is the same as that of this article in The Times.
This is the sub-heading.
Deaths this year are set to be a third higher than in 2018 with biggest increase among young women
These three paragraphs introduce the article.
Obesity and binge drinking are causing a surge in bowel cancer among young British adults, research shows.
Deaths in those aged under 50 are set to be about a third higher this year than in 2018, with the highest increase in young women.
Bowel cancer is the third most common cancer in the UK, after breast and prostate cancers, and there are 43,000 new cases and 16,000 deaths a year. More than nine in ten cases are in those over 50, but the disease is increasingly being diagnosed in those under 50, in whom it is more likely to be aggressive and deadly.
I am coeliac and whenever, I see some illness that is more common in females, I wonder, if this is down to the fact, that female coeliacs are more common than males. This page on the NHS web site flags it up with this sentence.
Reported cases of coeliac disease are higher in women than men.
This could be because coeliac disease can cause complications in pregnancy, so more women get tested.
The NHS web site also links coeliacs with bowel cancer, but it does say this.
Once you’ve been following a gluten-free diet for some time, your risk of developing these types of cancer is the same as that of the general population.
My son was an undiagnosed coeliac, who worked in the music business. He lived on a diet of ciggies, cannabis and Subways and contracted pancreatic cancer, which killed him at just 37.
He should have got himself tested, as the NHS says, that if you have a first degree relative (Me!), who has coeliac disease, then you should get tested.
So if you think, you have a problem with gluten, get yourself tested!
If not for yourself for your family!
I am surprised that the Italian lead researcher doesn’t mention coeliac disease as Italy has lots of it! All that pasta and pizza!
Potato Waste Used In New Hydrogen Production Research In P.E.I.
The title of this post, is the same as that of this article on Hydrogen Fuel News.
This is the sub-heading.
UPEI researchers are looking for new ways to produce hydrogen.
These are the first three paragraphs.
University of Prince Edward Island (UPEI) researchers have cooked up new hydrogen production recipes that include waste products like potato peelings, sawdust and tunicate.
An assistant professor in the Faculty of Sustainable Design Engineering at UPEI, Yulin Hu is one of a group of researchers seeking novel ways to generate hydrogen to replace fossil fuels and combat the effects of climate change.
One hydrogen production research project is focused on extracting H2 from potato peelings. The potato waste idea is especially notable due to Prince Edward Island (P.E.I.) being the Canadian province known for its potatoes.
Note.
Do the Canadians get their King Edwards from Prince Edward Island?
The potato is named after Edward VII according to its Wikipedia entry.
Tunicates are marine invertebrates.
This paragraph summarises some of the research.
The project involving sawdust is looking at utilizing sawdust to capture carbon dioxide. As for the one focused on tunicate, the idea behind that project is to synthesize tunicate waste, taking the waste and converting it into bio fertilizer.
The Canadian government must be impressed as they have given a six-figure grant for the research.
Conclusion
There’s some wacky research out there and some of it might be worth pursuing.
The Anonymous Widower 